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1082708

USP

二丁基羟基甲苯

United States Pharmacopeia (USP) Reference Standard

别名:

2,6-二- 叔-丁基-4-甲基苯酚, 2,6-二-叔丁基对甲酚, BHT, DBPC, 丁基化羟基甲苯, 丁基羟基甲苯

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关于此项目

线性分子式:
[(CH3)3C]2C6H2(CH3)OH
化学文摘社编号:
128-37-0
分子量:
220.35
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749182
EC Number:
204-881-4
Beilstein/REAXYS Number:
1911640
MDL number:
MFCD00011644
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grade

pharmaceutical primary standard

vapor density

7.6 (vs air)

vapor pressure

<0.01 mmHg ( 20 °C)

API family

butylated hydroxytoluene

form

crystalline powder

autoignition temp.

878 °F

manufacturer/tradename

USP

bp

265 °C (lit.)

mp

69-73 °C (lit.)

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

SMILES string

Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C

InChI

1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3

InChI key

NLZUEZXRPGMBCV-UHFFFAOYSA-N

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持，请访问现行药典网站。

Butylated hydroxytoluene (BHT) is a synthetic antioxidant commonly used in biologic formulations to prevent oxidative degradation. It acts as a preservative, protecting biologic products from oxidation, which can affect the potency and stability of sensitive molecules. Its application is critical in maintaining the integrity of biologics, particularly those that are exposed to air or light during production and storage.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

丁羟甲苯USP参考标准品，预期用途是USP规定的指定质量测试和检测。也用于USP各论，例如：
  • 度他雄胺和盐酸坦索罗辛胶囊

Analysis Note

这些产品仅供测试和化验使用。它们不适用于人类或动物，也不能用于诊断、治疗或治愈任何类型的疾病。

Other Notes

可能适用相应的销售限制。
该产品是美国药典生物制品计划的一部分。
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Ph

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pictograms

Environment
GHS09

signalword

Warning

hcodes

H410

存储类别

11 - Combustible Solids

flash_point_f

260.6 °F - open cup

flash_point_c

127 °C - open cup

Hazard Classifications

Aquatic Chronic 1

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene.
A L Branen
Journal of the American Oil Chemists' Society, 52(2), 59-63 (1975-02-01)
A M Malkinson
Environmental mutagenesis, 5(3), 353-362 (1983-01-01)
Although the average American's daily consumption of BHT can be measured in milligrams, there are numerous reports that BHT causes organ damage in laboratory animals. Only a few genotoxic effects of BHT have been reported, however, including mutagenicity in the
Butylated hydroxytoluene (BHT): a review.
H Babich
Environmental research, 29(1), 1-29 (1982-10-01)
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货号GTIN
1082708-500MG04061838681478