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1087803

USP

坎地沙坦酯

Name: 坎地沙坦酯
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

2-乙氧基-1-[[2′-(2H-四唑-5-基)[1,1′-联苯] -4-基]甲基] -1H-苯并咪唑-7-羧酸1-[[（（环己氧基）羰基]氧基]乙酯, TCV 116, TCY 116

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关于此项目

经验公式（希尔记法）:

C₃₃H₃₄N₆O₆

化学文摘社编号:

145040-37-5

分子量:

610.66

NACRES:

NA.24

PubChem Substance ID:

329749217

UNSPSC Code:

41116107

MDL number:

MFCD00871371

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属性

grade

pharmaceutical primary standard

API family

candesartan

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc4ccc(cc4)-c5ccccc5-c6nnn[nH]6

InChI

1S/C33H34N6O6/c1-3-42-32-34-28-15-9-14-27(31(40)43-21(2)44-33(41)45-24-10-5-4-6-11-24)29(28)39(32)20-22-16-18-23(19-17-22)25-12-7-8-13-26(25)30-35-37-38-36-30/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,35,36,37,38)

InChI key

GHOSNRCGJFBJIB-UHFFFAOYSA-N

Gene Information

human ... AGTR1(185)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Candesartan cilexetil USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:

Candesartan Cilexetil Tablets
Candesartan Cilexetil and Hydrochlorothiazide Tablets

Biochem/physiol Actions

坎地沙坦酯是一种非肽血管紧张素（AT2）受体拮抗剂。

坎地沙坦酯是有效的血管紧张素 II 受体拮抗剂坎地沙坦的前药形式。该前药在肠道内被酯酶裂解释，并放活性分子。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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pictograms

GHS08

signalword

Danger

hcodes

H360D,H373

pcodes

P202 - P260 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 1B - STOT RE 2 Oral

target_organs

Kidney,Blood

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c