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关于此项目
经验公式（希尔记法）:
C18H28N2O6S2
化学文摘社编号:
分子量:
432.55
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
grade
pharmaceutical primary standard
API family
captopril
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
S(SCC(C)C(=O)N2[C@@H](CCC2)C(=O)O)C[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)O
InChI
1S/C18H28N2O6S2/c1-11(15(21)19-7-3-5-13(19)17(23)24)9-27-28-10-12(2)16(22)20-8-4-6-14(20)18(25)26/h11-14H,3-10H2,1-2H3,(H,23,24)(H,25,26)/t11-,12?,13+,14+/m1/s1
InChI key
ZWKRXBCJAUKDCI-KRCVMZOZSA-N
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Captopril disulfide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Captopril Tablets
- Captopril
- Captopril and Hydrochlorothiazide Tablets
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Electrochemical reduction of disulfides.
H Kadin
Methods in enzymology, 143, 257-264 (1987-01-01)
O H Drummer et al.
European journal of clinical pharmacology, 32(3), 267-271 (1987-01-01)
We have measured the plasma concentrations of captopril and total disulfide conjugates of captopril after a 50 mg oral dose in 6 uraemic patients on maintenance dialysis and in 8 hypertensive subjects with normal renal function. The mean peak plasma
O H Drummer et al.
Biochemical pharmacology, 33(22), 3567-3571 (1984-11-15)
The absorption and metabolism of the disulfide dimer conjugate of captopril has been studied in the rat following both oral and intravenous dosing and compared with that of the active monomer, captopril. Metabolism of the dimer to captopril has been
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1091221-100MG | 04061838687951 |