grade
pharmaceutical primary standard
API family
cholecalciferol
manufacturer/tradename
USP
mp
83-86 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
−20°C
SMILES string
CC(C)CCC[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
InChI
1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13-/t21-,24+,25-,26+,27-/m1/s1
InChI key
QYSXJUFSXHHAJI-YRZJJWOYSA-N
Gene Information
human ... VDR(7421)
General description
本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持，请访问现行药典网站。
Application
胆钙化醇USP参考标准品，预期用途是USP规定的指定质量测试和检测。也用于USP各论，例如：
- 胆钙化醇溶液
- 胆钙化醇胶囊
- 胆钙化醇片
- 胆钙化醇咀嚼凝胶
- 含维生素 D 的钙片
- 油溶性维生素制剂
Biochem/physiol Actions
维生素 D 借以发挥作用的受体是配体依赖性转录因子超家族的成员。调控正常细胞和癌细胞的增殖和分化。对乳腺癌、结肠癌和前列腺癌细胞具有抗增殖和抗转移作用。肠和骨骼中的活化维生素 D 受体维持着钙的吸收和平衡。
维生素 D 通过调控正常细胞和癌细胞增殖和分化的受体而发挥作用。
Analysis Note
这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。
Other Notes
可能适用相应的销售限制。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
Cholecalciferol Tablets
United States Pharmacopeia, 43(2), 988-988 (2018)
Robert Scragg et al.
Hypertension (Dallas, Tex. : 1979), 64(4), 725-730 (2014-07-02)
Previous randomized controlled trials of vitamin D supplementation and blood pressure (BP) mainly have given vitamin D for short periods (<6 months) or at low doses (400 IU per day). This study aims to determine whether long-term high-dose vitamin D
Negar Tabatabaei et al.
The Journal of nutrition, 144(12), 1985-1993 (2014-10-17)
The effects of vitamin D during pregnancy on maternal and neonatal bone health remain unclear. This study was designed to test whether dietary vitamin D dose-dependently affects maternal and neonatal bone health. Female guinea pigs (n = 45; 4 mo
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1131009-5X30MG | 04061838700780 |