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1342106

USP

胰岛素人

Name: 胰岛素 人
Brand: USP

United States Pharmacopeia (USP) Reference Standard

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关于此项目

经验公式（希尔记法）:

C₂₅₇H₃₈₃N₆₅O₇₇S₆

化学文摘社编号:

11061-68-0

分子量:

5807.57

UNSPSC Code:

41116107

NACRES:

NA.24

MDL number:

MFCD00131380

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属性

grade

pharmaceutical primary standard

API family

insulin

form

solid

manufacturer/tradename

USP

application(s)

USP Biologics
pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

InChI key

PBGKTOXHQIOBKM-FHFVDXKLSA-N

说明

General description

Insulin Human is a recombinant form of the human insulin hormone, comprising two polypeptide chains (A and B) linked by disulfide bonds. It regulates glucose metabolism and is essential in the management of diabetes mellitus.

The USP biologics proteins category provides critical standards and reference materials necessary for the development and manufacturing of therapeutic proteins. These proteins, which can be naturally derived or genetically engineered, are essential in treating various diseases and conditions, ensuring that they meet quality, safety, and efficacy standards.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

人胰岛素USP适用于美国药典(USP)规定的质量测试和分析。
也适用于USP专论方法：

人胰岛素注射液
低鱼精蛋白锌人胰岛素混悬液和人胰岛素注射液
低鱼精蛋白锌人胰岛素混悬液

Biochem/physiol Actions

可调节细胞对葡萄糖、氨基酸和脂肪酸的摄取、利用和储存，并抑制糖原、蛋白质和脂肪的分解。

由胰岛β-细胞所产生的二链多肽激素。其分子量为~5800 Da。α链和β链是由两个链间二硫键所连接的。α链含有一个链间二硫键。胰岛素可调节细胞对葡萄糖、氨基酸和脂肪酸的摄取、利用和储存，并抑制糖原、蛋白质和脂肪的分解。

Analysis Note

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。

Other Notes

InChI：1S/C257H383N65O77S6/c1-29-131(23)205(313-193(339)104-259)252(393)317-204(130(21)22)248(389)288-159(75-82-200(349)350)217(358)282-156(71-78-189(263)335)221(362)308-183-116-403-404-117-184-243(384)305-178(111-324)240(381)294-162(88-123(7)8)225(366)295-168(95-140-53-61-146(329)62-54-140)228(369)283-154(69-76-187(261)333)218(359)290-161(87-122(5)6)223(364)285-158(74-81-199(347)348)220(361)302-174(101-190(264)336)235(376)298-170(97-142-57-65-148(331)66-58-142)231(372)309-182(242(383)304-176(255(396)397)103-192(266)338)115-402-401-114-181(214(355)273-107-194(340)278-153(72-79-197(343)344)216(357)281-151(51-42-84-271-257(267)268)212(353)272-108-195(341)279-166(93-138-46-36-32-37-47-138)227(368)297-167(94-139-48-38-33-39-49-139)230(371)299-171(98-143-59-67-149(332)68-60-143)238(379)320-208(135(27)327)254(395)322-85-43-52-186(322)246(387)286-152(50-40-41-83-258)222(363)321-209(136(28)328)256(398)399)311-250(391)203(129(19)20)316-236(377)164(90-125(11)12)292-229(370)169(96-141-55-63-147(330)64-56-141)296-224(365)160(86-121(3)4)289-210(351)133(25)277-215(356)157(73-80-198(345)346)287-247(388)202(128(17)18)315-237(378)165(91-126(13)14)293-233(374)173(100-145-106-270-120-276-145)301-239(380)177(110-323)280-196(342)109-274-213(354)180(113-400-405-118-185(310-244(183)385)245(386)319-207(134(26)326)253(394)306-179(112-325)241(382)318-206(132(24)30-2)251(392)312-184)307-226(367)163(89-124(9)10)291-232(373)172(99-144-105-269-119-275-144)300-219(360)155(70-77-188(262)334)284-234(375)175(102-191(265)337)303-249(390)201(127(15)16)314-211(352)150(260)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-209,323-332H,29-30,40-43,50-52,69-104,107-118,258-260H2,1-28H3,(H2,261,333)(H2,262,334)(H2,263,335)(H2,264,336)(H2,265,337)(H2,266,338)(H,269,275)(H,270,276)(H,272,353)(H,273,355)(H,274,354)(H,277,356)(H,278,340)(H,279,341)(H,280,342)(H,281,357)(H,282,358)(H,283,369)(H,284,375)(H,285,364)(H,286,387)(H,287,388)(H,288,389)(H,289,351)(H,290,359)(H,291,373)(H,292,370)(H,293,374)(H,294,381)(H,295,366)(H,296,365)(H,297,368)(H,298,376)(H,299,371)(H,300,360)(H,301,380)(H,302,361)(H,303,390)(H,304,383)(H,305,384)(H,306,394)(H,307,367)(H,308,362)(H,309,372)(H,310,385)(H,311,391)(H,312,392)(H,313,339)(H,314,352)(H,315,378)(H,316,377)(H,317,393)(H,318,382)(H,319,386)(H,320,379)(H,321,363)(H,343,344)(H,345,346)(H,347,348)(H,349,350)(H,396,397)(H,398,399)(H4,267,268,271)/t131-,132-,133-,134+,135+,136+,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-,209-/m0/s1

可能适用相应的销售限制。

该产品是美国药典生物制品计划的一部分。

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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

兴奋剂肽类激素

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Isophane Insulin Human Suspension

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 44(4), 2352-2352 (2019)

全球贸易项目编号

货号	GTIN
1342106-100MG	04061838729910

主要文件

胰岛素人

United States Pharmacopeia (USP) Reference Standard

选择尺寸

关于此项目

grade

API family

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manufacturer/tradename

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InChI key

General description

Application

Biochem/physiol Actions

Analysis Note

Other Notes

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安全信息

存储类别

flash_point_f

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法规信息

文件

分析证书(COA)

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全球贸易项目编号

主要文件

胰岛素 人

United States Pharmacopeia (USP) Reference Standard

选择尺寸

关于此项目

grade

API family

form

manufacturer/tradename

application(s)

format

storage temp.

InChI key

General description

Application

Biochem/physiol Actions

Analysis Note

Other Notes

Still not finding the right product?

安全信息

存储类别

flash_point_f

flash_point_c

法规信息

文件

分析证书(COA)

已有该产品？

同行评审论文

全球贸易项目编号

胰岛素人