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1365065

USP

左旋甲状腺素钠

Name: 左旋甲状腺素钠
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

左旋甲状腺素钠水合物, 3,3′,5,5′-四碘代-L-甲状腺原氨酸单钠盐水合物, O-(4-羟基-3,5-二碘代苯基)-3,5-二碘代-L-酪氨酸钠水合物

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关于此项目

经验公式（希尔记法）:

C₁₅H₁₀I₄NNaO₄ · xH₂O

化学文摘社编号:

25416-65-3

分子量:

798.85 (anhydrous basis)

NACRES:

NA.24

PubChem Substance ID:

329750053

UNSPSC Code:

41116107

MDL number:

MFCD06408007

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属性

grade

pharmaceutical primary standard

API family

levothyroxine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;1H2/q;+1;/p-1/t12-;;/m0../s1

InChI key

ANMYAHDLKVNJJO-LTCKWSDVSA-M

Gene Information

human ... THRA(7067), THRB(7068)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Levothyroxine sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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pictograms

GHS08

signalword

Danger

hcodes

H372

pcodes

P260 - P264 - P270 - P314 - P501

Hazard Classifications

STOT RE 1

target_organs

Thyroid,Cardio-vascular system,Kidney

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Impact of hydration state and molecular oxygen on the chemical stability of levothyroxine sodium.

Mazen Lee Hamad et al.

Pharmaceutical development and technology, 20(3), 314-319 (2013-12-04)

Levothyroxine sodium is an important medication used primarily for treating patients with hypothyroidism. Levothyroxine sodium tablets have been recalled many times since their 1955 introduction to the US market. These recalls resulted from the failure of lots to meet their

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货号	GTIN
1365065-50MG	04061838702340