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Merck
CN

1366002

USP

利多卡因

United States Pharmacopeia (USP) Reference Standard

别名:

2-二乙氨基-N-(2,6-二甲苯基)乙酰胺, 利多卡因, 赛洛卡因

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关于此项目

经验公式(希尔记法):
C14H22N2O
化学文摘社编号:
分子量:
234.34
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

lidocaine

manufacturer/tradename

USP

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)

InChI key

NNJVILVZKWQKPM-UHFFFAOYSA-N

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息,包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持,请访问现行药典网站。

Application

利多卡因USP参考标准品用于指定质量测试和分析。

还可用于制备标准和系统适用性溶液,用于根据以下美国药典(USP)各论进行测定、鉴定和杂质分析:
  • 利多卡因
  • 盐酸利多卡因外用溶液
  • 盐酸利多卡因口服外用溶液
  • 盐酸利多卡因胶浆

Biochem/physiol Actions

Na+通道阻滞剂;IB类抗心律失常药。
Na+通道阻滞剂;在肠胃外给药后可迅速被吸收的IB类抗心律失常药。

Analysis Note

这些产品仅供测试和化验使用。它们不适用于人类或动物,也不能用于诊断、治疗或治愈任何类型的疾病。

Other Notes

可能适用相应的销售限制。


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Lidocaine Hydrochloride Jelly
United States Pharmacopeia, 43(6), 2625-2625 (2020)
Daniela Casoni et al.
Veterinary anaesthesia and analgesia, 42(3), 250-259 (2014-07-22)
To determine the potency ratio between S-ketamine and racemic ketamine as inductive agents for achieving tracheal intubation in dogs. Prospective, randomized, 'blinded', clinical trial conducted in two consecutive phases. 112 client-owned dogs (ASA I or II). All animals were premedicated
Song-Young Park et al.
American journal of physiology. Heart and circulatory physiology, 307(3), H346-H352 (2014-06-08)
Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial respiration. Therefore, the present study examined mitochondrial respiratory rates in smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscles.



全球贸易项目编号

货号GTIN
1366002-250MG04061838731364