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1457902

USP

Nefazodone hydrochloride

Name: Nefazodone hydrochloride
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl- 2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one hydrochloride, BMY-13754, MJ-13754-1, Serzone

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关于此项目

经验公式（希尔记法）:

C₂₅H₃₂ClN₅O₂ · HCl

化学文摘社编号:

82752-99-6

分子量:

506.47

NACRES:

NA.24

PubChem Substance ID:

329750537

UNSPSC Code:

41116107

MDL number:

MFCD00935760

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属性

grade

pharmaceutical primary standard

API family

nefazodone

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CCOC4=CC=CC=C4.Cl

InChI

1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H

InChI key

DYCKFEBIOUQECE-UHFFFAOYSA-N

Gene Information

human ... HTR2A(3356), HTR2C(3358), SLC6A2(6530), SLC6A4(6532)

说明

Application

Nefazodone hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Nefazodone Hydrochloride Tablets

Biochem/physiol Actions

Novel antidepressant; mixed 5-HT_2A serotonin receptor antagonist/serotonin uptake inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Electrochemical characterisation of nefazodone hydrochloride and voltammetric determination of the drug in pharmaceuticals and human serum.

Uslu, Bengi, and Sibel A. Ozkan.

Analytica Chimica Acta, 462.1, 49-57 (2002)

Systematic evaluation of commercially available ultra-high performance liquid chromatography columns for drug metabolite profiling: optimization of chromatographic peak capacity.

Anne-Charlotte Dubbelman et al.

Journal of chromatography. A, 1374, 122-133 (2014-12-02)

The present study investigated the practical use of modern ultra-high performance liquid chromatography (UHPLC) separation techniques for drug metabolite profiling, aiming to develop a widely applicable, high-throughput, easy-to-use chromatographic method, with a high chromatographic resolution to accommodate simultaneous qualitative and

全球贸易项目编号

货号	GTIN
1457902-200MG	04061833852422