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1559006

USP

强的松

Name: 强的松
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

1-可的松, 17Α,21-二羟基-1,4-孕甾二烯-3,11,20-三酮, 去氢可的松, 强的松

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关于此项目

经验公式（希尔记法）:

C₂₁H₂₆O₅

化学文摘社编号:

53-03-2

分子量:

358.43

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329750938

MDL number:

MFCD00003608

Beilstein/REAXYS Number:

2065301

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属性

grade

pharmaceutical primary standard

API family

prednisone

manufacturer/tradename

USP

mp

236-238 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O=C1C=C[C@@]2(C)C(CC[C@]([C@@](CC[C@@]3(C(CO)=O)O)([H])[C@]3(C)C4)([H])[C@]2([H])C4=O)=C1

InChI

1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1

InChI key

XOFYZVNMUHMLCC-ZPOLXVRWSA-N

Gene Information

human ... NR3C1(2908)

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Prednisone USP reference standard for specified quality tests and assay use.

Also used to prepare standard, standard stock and internal standard solutions for the assay and performance tests according to the given below monographs of United States Pharmacopeia (USP):

Prednisone
Prednisone Tablets
Prednisone Oral Solution
Hydrocortisone Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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pictograms

GHS08

signalword

Warning

hcodes

H373

pcodes

P260 - P314 - P501

Hazard Classifications

STOT RE 2

存储类别

11 - Combustible Solids

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Prednisone Oral Solution

United States Pharmacopeia and National Formulary

United States Pharmacopeia, 30(1), 3671-3671 (2020)

Rheumatoid arthritis during pregnancy and postnatal catch-up growth in the offspring.

Florentien D O de Steenwinkel et al.

Arthritis & rheumatology (Hoboken, N.J.), 66(7), 1705-1711 (2014-03-01)

Active rheumatoid arthritis (RA) during pregnancy and the presence of rheumatoid factor (RF) or anti-citrullinated protein antibodies (ACPAs) are associated with lower birth weight of the child. Moreover, treatment of the mothers with prednisone may shorten the gestational age at

Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based therapy: ELM-PC 5.

Karim Fizazi et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(7), 723-731 (2015-01-28)

Orteronel (TAK-700) is an investigational, nonsteroidal, reversible, selective 17,20-lyase inhibitor. This study examined orteronel in patients with metastatic castration-resistant prostate cancer that progressed after docetaxel therapy. In our study, 1,099 men were randomly assigned in a 2:1 schedule to receive

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全球贸易项目编号

货号	GTIN
1559006-250MG	04061838742322