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Merck
CN

1598405

USP

雷尼替丁 盐酸盐

United States Pharmacopeia (USP) Reference Standard

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关于此项目

经验公式(希尔记法):
C13H22N4O3S · HCl
化学文摘社编号:
分子量:
350.86
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
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grade

pharmaceutical primary standard

API family

ranitidine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl[H].CN\C(NCCSCc1ccc(CN(C)C)o1)=C\[N+]([O-])=O

InChI

1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9-;

InChI key

GGWBHVILAJZWKJ-CHHCPSLASA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ranitidine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monographs such as:
  • Ranitidine Injection
  • Ranitidine Tablets
  • Ranitidine in Sodium Chloride Injection
  • Ranitidine Oral Solution

Biochem/physiol Actions

H2 组胺受体拮抗剂;抗溃疡剂。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Question 1: does the use of ranitidine increase the risk of NEC in preterm infants?
Manigandan Chandrasekaran et al.
Archives of disease in childhood, 99(4), 390-392 (2014-03-15)
T S Gaginella et al.
Drug intelligence & clinical pharmacy, 17(12), 873-885 (1983-12-01)
Ranitidine is a selective, competitive histamine H2-receptor antagonist recently approved by the Food and Drug Administration for use in the short-term treatment of active duodenal ulcers and gastric hypersecretory conditions. Ranitidine is four to ten times more potent than cimetidine
M B Evans et al.
Journal of pharmaceutical and biomedical analysis, 7(1), 1-22 (1989-01-01)
The selection, development, definition and validation of selective stability-indicating procedures for high-performance liquid chromatographic and thin-layer chromatographic analyses of ranitidine hydrochloride are described. The procedures used in conjunction can be applied to the quality assurance and stability assessments of both



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货号GTIN
1598405-200MG04061838744784