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Merck
CN

1607007

USP

糖精

United States Pharmacopeia (USP) Reference Standard

别名:

2,3-二羟基-1,2-苯并异噻唑基-3-酮-1,1-二氧化物, 2-磺基苯甲酸亚胺, 邻磺酰苯酰亚胺

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关于此项目

经验公式(希尔记法):
C7H5NO3S
化学文摘社编号:
分子量:
183.18
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6888
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grade

pharmaceutical primary standard

API family

saccharin

manufacturer/tradename

USP

mp

226-229 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C1NS(=O)(=O)c2ccccc12

InChI

1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)

InChI key

CVHZOJJKTDOEJC-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Saccharin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Saccharin Sodium Tablets

Biochem/physiol Actions

哺乳动物的甜促味剂。有人提出,果蝇具有葡萄糖特异性甘油味觉受体结合位点。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


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存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The toxicological effects of saccharin in short-term genotoxicity assays.
D L Arnold et al.
Mutation research, 221(2), 69-132 (1989-09-01)
M D Reuber
Environmental health perspectives, 25, 173-200 (1978-08-01)
Saccharin is carcinogenic for the urinary bladder in rats and mice, and most likely is carcinogenic in human beings. The neoplasms of the urinary bladder are malignant and invade and metastasize. Male rats are more susceptible to urinary bladder carcinogenesis
D L Arnold
Fundamental and applied toxicology : official journal of the Society of Toxicology, 4(5), 674-685 (1984-10-01)
Saccharin, like most of the artificial sweeteners, was discovered quite by accident. The controversy regarding its use as a food additive is reflected by the number of chronic/carcinogenic studies conducted to assess its safety. Two chronic studies were conducted prior



全球贸易项目编号

货号GTIN
1607007-200MG04061835345564