grade
reagent grade
product line
Vetec™
assay
98%
mp
128-132 °C (lit.)
SMILES string
CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI
1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
InChI key
RJKFOVLPORLFTN-LEKSSAKUSA-N
Gene Information
human ... PGR(5241)
Biochem/physiol Actions
孕酮是维持妊娠的激素。它对几乎所有哺乳动物的胚胎形成、发育和存活都是必不可少的。这种激素通过孕激素受体发挥作用,孕激素受体在整个妊娠期特异表达于子宫内膜间质。已知它通过肌肉注射给药可预防早产。
诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。
诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。 孕激素与乳腺癌发病有关。
Other Notes
黄体分泌的类固醇激素。
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
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signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Lact. - Repr. 1A
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Biology of progesterone action during pregnancy recognition and maintenance of pregnancy.
Spencer T E and Bazer F W
Frontiers in Bioscience, 7(1-3), d1879-d1898 (2002)
Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study.
da Fonseca E B, et al.
American Journal of Obstetrics and Gynecology, 188(2), 419-424 (2003)
Rudolf Kaaks et al.
International journal of cancer, 134(8), 1947-1957 (2013-10-25)
Results from prospective studies on premenopausal serum hormone levels in relation to breast cancer risk have been inconclusive, especially with regard to tumor subtypes. Using a case-control study nested within the prospective European Prospective Investigation into Cancer and Nutrition (EPIC)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| V900699-25G | 04061832868776 |
| V900699-5G | 04061832868783 |
