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Merck
CN

V900699

黄体酮

Vetec, reagent grade, 98%

别名:

4-孕烯-3,20-二酮

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关于此项目

经验公式(希尔记法):
C21H30O2
化学文摘社编号:
分子量:
314.46
EC Number:
200-350-6
UNSPSC Code:
51111800
PubChem Substance ID:
Beilstein/REAXYS Number:
1915950
MDL number:
Assay:
98%
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grade

reagent grade

product line

Vetec

assay

98%

mp

128-132 °C (lit.)

SMILES string

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1

InChI key

RJKFOVLPORLFTN-LEKSSAKUSA-N

Gene Information

human ... PGR(5241)

Biochem/physiol Actions

孕酮是维持妊娠的激素。它对几乎所有哺乳动物的胚胎形成、发育和存活都是必不可少的。这种激素通过孕激素受体发挥作用,孕激素受体在整个妊娠期特异表达于子宫内膜间质。已知它通过肌肉注射给药可预防早产。
诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。
诱导子宫内皮细胞的成熟和分泌活性;抑制排卵。 孕激素与乳腺癌发病有关。

Other Notes

黄体分泌的类固醇激素。

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Biology of progesterone action during pregnancy recognition and maintenance of pregnancy.
Spencer T E and Bazer F W
Frontiers in Bioscience, 7(1-3), d1879-d1898 (2002)
Prophylactic administration of progesterone by vaginal suppository to reduce the incidence of spontaneous preterm birth in women at increased risk: a randomized placebo-controlled double-blind study.
da Fonseca E B, et al.
American Journal of Obstetrics and Gynecology, 188(2), 419-424 (2003)
Rudolf Kaaks et al.
International journal of cancer, 134(8), 1947-1957 (2013-10-25)
Results from prospective studies on premenopausal serum hormone levels in relation to breast cancer risk have been inconclusive, especially with regard to tumor subtypes. Using a case-control study nested within the prospective European Prospective Investigation into Cancer and Nutrition (EPIC)



全球贸易项目编号

货号GTIN
V900699-25G04061832868776
V900699-5G04061832868783