E6510
Ergosterol
≥75%
Synonym(s):
3β-Hydroxy-5,7,22-ergostatriene, 5,7,22-Ergostatrien-3β-ol, Provitamin D2
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About This Item
Empirical Formula (Hill Notation):
C28H44O
CAS Number:
Molecular Weight:
396.65
UNSPSC Code:
12352205
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-352-7
Beilstein/REAXYS Number:
2338604
MDL number:
biological source
microbial
Quality Level
assay
≥75%
form
powder
color
white to off-white
mp
156-158 °C (lit.)
storage temp.
2-8°C
SMILES string
[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
InChI
1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
InChI key
DNVPQKQSNYMLRS-APGDWVJJSA-N
General description
Ergosterol or provitamin D2 is a biological precursor of Vitamin D2. It is found predominantly in cell membranes of fungi and protists such as trypanosomes.
Application
Ergosterol has been used:
- as a component of yeast cell monolayer models, to study the effects of steroidal and triterpenoid saponins on the monolayers
- as a standard sample, to isolate and identify a fungal metabolite fraction containing ergosterol
- as a component of the culture medium to isolate the CYP51RNAi phenotype of Trypanosoma brucei gambiense, to verify ergosterol biosynthesis
Biochem/physiol Actions
Ergosterol has a role in maintaining the integrity of the cell membrane and its fluidity. The sterol has anti-tumor and anti-inflammatory properties.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| E6510-10G | 04061833604540 |
| E6510-25G | 04061833076378 |
| E6510-5G | 04061833604557 |