100277
Adamantane
≥99%
Synonym(s):
Tricyclo[3.3.1.13,7]decane
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About This Item
Empirical Formula (Hill Notation):
C10H16
CAS Number:
Molecular Weight:
136.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-001-4
Beilstein/REAXYS Number:
1901173
MDL number:
Assay:
≥99%
Form:
solid
Quality Level
assay
≥99%
form
solid
mp
209-212 °C (subl.) (lit.)
SMILES string
C1[C@H]2C[C@H]3C[C@@H]1C[C@@H](C2)C3
InChI
1S/C10H16/c1-7-2-9-4-8(1)5-10(3-7)6-9/h7-10H,1-6H2/t7-,8+,9-,10+
InChI key
ORILYTVJVMAKLC-YNFQOJQRSA-N
Application
Adamantane is the structural backbone of various medicinally important compounds such as amantadine, memantine, saxagliptin and vildagliptin. It is used in the synthesis of adamantine-based dirhodium tetracarboxylate catalyst for carbenoid reactions. It can also be used as a seeding material for the nucleation of nanocrystalline diamond films.
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Ayako Takahashi et al.
American journal of physiology. Heart and circulatory physiology, 304(10), H1361-H1369 (2013-03-19)
Incretin hormones, including glucagon-like peptide-1 (GLP-1), a target for diabetes mellitus (DM) treatment, are associated with cardioprotection. As dipeptidyl-peptidase IV (DPP-IV) inhibition increases plasma GLP-1 levels in vivo, we investigated the cardioprotective effects of the DPP-IV inhibitor vildagliptin in a
Benjamin M Scirica et al.
The New England journal of medicine, 369(14), 1317-1326 (2013-09-03)
The cardiovascular safety and efficacy of many current antihyperglycemic agents, including saxagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor, are unclear. We randomly assigned 16,492 patients with type 2 diabetes who had a history of, or were at risk for, cardiovascular
Nucleation enhancement of nanocrystalline diamond growth at low substrate temperatures by adamantane seeding.
Tsugawa K, et al.
The Journal of Physical Chemistry C, 114(9), 3822-3824 (2010)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 100277-25G | 04061838661845 |
| 100277-100G | 04061838661838 |