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Merck
CN

107263

5-Hydroxy-2-methylpyridine

99%

Synonym(s):

6-Methyl-3-pyridinol

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About This Item

Empirical Formula (Hill Notation):
C6H7NO
CAS Number:
Molecular Weight:
109.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
214-337-8
MDL number:
Assay:
99%
Form:
solid
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Quality Level

assay

99%

form

solid

mp

168-170 °C (lit.)

solubility

dichloromethane: soluble

SMILES string

Cc1ccc(O)cn1

InChI

1S/C6H7NO/c1-5-2-3-6(8)4-7-5/h2-4,8H,1H3

InChI key

DHLUJPLHLZJUBW-UHFFFAOYSA-N

Application

  • 5-Hydroxy-2-methylpyridine was used as starting reagent for the synthesis of 5-[(4-methoxybenzyl)oxy]-2-pyridinecarbaldehyde.
  • It was used in synthesis of [HNC6H6OH]2[Cu(NC5H5)4(NbOF5)2].
  • It was used as ligand of a platinum complex which showed protein kinase inhibitory action at nanomolar levels.
  • It forms a chiral pyridinium ionic liquid on reaction with L-menthol chloromethyl ether.


pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Tetrahedron Asymmetry, 17, 1728-1728 (2006)
Synthesis of (R)-(+)-methyl 3-amino-3-(5-hydroxy-2-pyridinyl) propanoate, an analog of l-azatyrosine.
Adamczy M and Reddy RE.
Tetrahedron Asymmetry, 12(7), 1047-1054 (2001)
Douglas S Williams et al.
Inorganic chemistry, 46(8), 2944-2946 (2007-03-23)
A pyridocarbazole platinum complex, which matches the overall shape of the natural product staurosporine, binds with high affinity at the adenosine triphosphate binding site of glycogen synthase kinase 3 (GSK-3alpha).



Global Trade Item Number

SKUGTIN
107263-25G04061838674715
107263-100G04061833070703