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Merck
CN

128708

trans-Ferulic acid

99%

Synonym(s):

trans-4-Hydroxy-3-methoxycinnamic acid, Ferulic acid

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About This Item

Linear Formula:
HOC6H3(OCH3)CH=CHCO2H
CAS Number:
Molecular Weight:
194.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-679-7
Beilstein/REAXYS Number:
1570363
MDL number:
Assay:
99%
Form:
powder, powder and chunks
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Quality Level

assay

99%

form

powder, powder and chunks

mp

168-172 °C (lit.)

functional group

carboxylic acid

SMILES string

OC(/C=C/C1=CC(OC)=C(O)C=C1)=O

InChI

1S/C10H10O4/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13/h2-6,11H,1H3,(H,12,13)/b5-3+

InChI key

KSEBMYQBYZTDHS-HWKANZROSA-N

Application

trans-Ferulic acid was used for esterification of methacrylated dextran. It was also used to study the effect of oral administration of trans-ferulic acid to c57BL mice on ethanol-induced liver injury. Furthermore, it has been used in the synthesis of new biocompatible antioxidant polymers linking trans-ferulic acid.

Biochem/physiol Actions

Hydroxycinnamic acid found in plant-based foods. Antioxidant.


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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Chatchawan Chotimarkorn et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 15(11), 951-958 (2008-04-22)
The effects of the oral administration of trans-ferulic acid and gamma-oryzanol (mixture of steryl ferulates) with ethanol (5.0 g per kg) for 30 days to c57BL mice on ethanol-induced liver injury were investigated. Preventions of ethanol-induced liver injury by trans-ferulic
Roberta Cassano et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 72(1), 232-238 (2008-11-04)
Long-term exposure of the skin to UV light causes degenerative effects, which can be minimized by using antioxidant formulations. The major challenge in this regard is that a significant amount of antioxidant should reach at the site for effective photoprotection.
Nickolas A Anderson et al.
The Plant cell, 27(8), 2195-2209 (2015-08-13)
Modifying lignin composition and structure is a key strategy to increase plant cell wall digestibility for biofuel production. Disruption of the genes encoding both cinnamyl alcohol dehydrogenases (CADs), including CADC and CADD, in Arabidopsis thaliana results in the atypical incorporation



Global Trade Item Number

SKUGTIN
128708-100G04061838725882
128708-25G04061835281367
128708-5G04061835281374