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144088

4-Hydroxybenzaldehyde

Name: 4-Hydroxybenzaldehyde
Brand: ALDRICH

98%

Synonym(s):

4-Formylphenol, 4-Hydroxybenzaldehyde, Parahydroxybenzaldehyde, p-Formylphenol, p-Hydroxybenzaldehyde, p-Oxybenzaldehyde

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About This Item

Linear Formula:

HOC₆H₄CHO

CAS Number:

123-08-0

Molecular Weight:

122.12

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24848630

EC Number:

204-599-1

Beilstein/REAXYS Number:

471352

MDL number:

MFCD00006939

Assay:

98%

Form:

solid

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Properties

Quality Level

200

assay

98%

form

solid

mp

112-116 °C (lit.)

functional group

aldehyde

SMILES string

[H]C(=O)c1ccc(O)cc1

InChI

1S/C7H6O2/c8-5-6-1-3-7(9)4-2-6/h1-5,9H

InChI key

RGHHSNMVTDWUBI-UHFFFAOYSA-N

Description

Application

4-Hydroxybenzaldehyde can be used as a reactant to synthesize:

Schiff Bases with optical properties through its reaction with anilines.
Vanillin via bromination followed by copper-catalyzed coupling reaction with sodium methoxide.
Oligo-4-hydroxybenzaldehyde by an oxidative polycondensation reaction with hydrogen peroxide (H₂O₂) in an alkaline medium.

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pictograms

GHS05,GHS07

signalword

Danger

hcodes

H318,H335

pcodes

P261 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338 - P403 + P233

Hazard Classifications

Eye Dam. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

345.2 °F

flash_point_c

174 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Vanillin synthesis from 4-hydroxybenzaldehyde

Taber Douglass F, et al.

Journal of Chemical Education, 84(7), 1158-1158 (2007)

Gastrodia elata Blume water extracts improve insulin resistance by decreasing body fat in diet-induced obese rats: vanillin and 4-hydroxybenzaldehyde are the bioactive candidates.

Sunmin Park et al.

European journal of nutrition, 50(2), 107-118 (2010-06-26)

Insulin resistance is a common symptom of metabolic diseases such as obesity, type 2 diabetes and hyperlipidemia. We investigated whether Gastrodia elata Blume water extract(GEB), containing phenolic compounds, had a beneficial action on insulin resistance in male Sprague-Dawley rats fed

Hypomethylating agents (HMAs) effect on myelodysplastic/myeloproliferative neoplasm unclassifiable (MDS/MPN-U): single institution experience.

Aref Al-Kali et al.

Leukemia & lymphoma, 1-3 (2018-02-22)

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Global Trade Item Number

SKU	GTIN
144088-250G	04061835052219
144088-50G	04061835048403