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145726

DL-Tyrosine

Name: <SC>DL</SC>-Tyrosine
Brand: ALDRICH

99%

Synonym(s):

(±)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-DL-alanine

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About This Item

Linear Formula:

4-(HO)C₆H₄CH₂CH(NH₂)COOH

CAS Number:

556-03-6

Molecular Weight:

181.19

UNSPSC Code:

12352209

NACRES:

NA.22

PubChem Substance ID:

24848742

EC Number:

209-113-1

Beilstein/REAXYS Number:

515881

MDL number:

MFCD00063074

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Properties

Quality Level

100

assay

99%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

≥300 °C (lit.)

application(s)

peptide synthesis

SMILES string

NC(Cc1ccc(O)cc1)C(O)=O

InChI

1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)

InChI key

OUYCCCASQSFEME-UHFFFAOYSA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.

Shannon L Maude et al.

Blood, 125(11), 1759-1767 (2015-02-04)

Early T-cell precursor (ETP) acute lymphoblastic leukemia (ALL) is a recently described subtype of T-ALL characterized by a unique immunophenotype and genomic profile, as well as a high rate of induction failure. Frequent mutations in cytokine receptor and Janus kinase

Guidelines for pre-clinical animal and cellular models of MuSK-myasthenia gravis.

W D Phillips et al.

Experimental neurology, 270, 29-40 (2014-12-30)

Muscle-specific tyrosine kinase (MuSK) autoantibodies are the hallmark of a form of myasthenia gravis (MG) that can challenge the neurologist and the experimentalist. The clinical disease can be difficult to treat effectively. MuSK autoantibodies affect the neuromuscular junction in several

F604S exchange in FIP1L1-PDGFRA enhances FIP1L1-PDGFRA protein stability via SHP-2 and SRC: a novel mode of kinase inhibitor resistance.

S P Gorantla et al.

Leukemia, 29(8), 1763-1770 (2015-03-13)

FIP1L1-PDGFRA is a constitutively activated kinase described in chronic eosinophilic leukemia (CEL) and hypereosinophilic syndrome (HES). Imatinib is clinically active in FIP1L1-PDGFRA-positive diseases. Using in vitro screening to identify imatinib-resistant mutations, we frequently detected a Phe to Ser exchange at

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Global Trade Item Number

SKU	GTIN
145726-100G	04061833544549
145726-25G	04061838736352