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Merck
CN

154563

Tris Base

≥99.9%, solid, ultrapure grade

Synonym(s):

Tris Base, Tris(hydroxymethyl)aminomethane, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol

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About This Item

Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
PubChem Substance ID:
UNSPSC Code:
12352104
EC Number:
201-064-4
MDL number:
Beilstein/REAXYS Number:
741883
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Product Name

Tris(hydroxymethyl)aminomethane, ultrapure grade, ≥99.9%

grade

ultrapure grade

assay

≥99.9%

form

solid

useful pH range

7-9

pKa (25 °C)

8.1

bp

219-220 °C/10 mmHg (lit.)

mp

167-172 °C (lit.)

solubility

water: 0.66 g/mL, clear, colorless

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

Application

Buffer and primary pH standard. pKa=8.3 at 20°C. Auxiliary material in pharmaceutical science.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Chimica Oggi, 12, 24-24 (1994)
Chem. Abstr., 121, 212675r-212675r (1994)
Aldrichimica Acta, 16, 35-35 (1983)