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17308

N,N-Dimethylacetamide

suitable for peptide synthesis, ≥99.8% (GC)

Synonym(s):

DMA, DMAc, Dimethylacetamide

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About This Item

Linear Formula:
CH3CON(CH3)2
CAS Number:
127-19-5
Molecular Weight:
87.12
UNSPSC Code:
12352111
NACRES:
NA.22
PubChem Substance ID:
57647631
EC Number:
204-826-4
Beilstein/REAXYS Number:
1737614
MDL number:
MFCD00008686
Assay:
≥99.8% (GC)
Technique(s):
GC/GC: suitable
Bp:
164.5-166 °C (lit.)
Vapor pressure:
2 mmHg ( 25 °C), 4 mmHg ( 38 °C)
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vapor density

3 (vs air)

Quality Level

100

vapor pressure

2 mmHg ( 25 °C), 4 mmHg ( 38 °C)

assay

≥99.8% (GC)

form

liquid

autoignition temp.

914 °F

expl. lim.

1.8 %, 100 °F, 11.5 %, 160 °F

technique(s)

GC/GC: suitable

impurities

≤0.02% water

refractive index

n20/D 1.437 (lit.), n20/D 1.438

pH

4 (20 °C, 200 g/L)

bp

164.5-166 °C (lit.)

mp

−20 °C (lit.)

density

0.937 g/mL at 25 °C (lit.)

suitability

in accordance for amine test

application(s)

peptide synthesis

SMILES string

CN(C)C(C)=O

InChI

1S/C4H9NO/c1-4(6)5(2)3/h1-3H3

InChI key

FXHOOIRPVKKKFG-UHFFFAOYSA-N

Application

N,N-Dimethylacetamide (DMA) can be used as a solvent in peptide synthesis.

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pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 2

flash_point_f

147.2 °F - closed cup

flash_point_c

64 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF5944
BCCB9376
BCCB6240
BCBZ5573
BCBW6289

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Total synthesis of the thiazolyl peptide GE2270 A
Muller HM, et al.
Angewandte Chemie (International Edition in English), 46(25), 4771-4774 (2007)
Peptides derived from nucleoside β-amino acids form an unusual 8-helix
Threlfall R, et al.
Chemical Communications (Cambridge, England), 46(5), 585-587 (2008)
The Horner-Wadsworth-Emmons reaction in the synthesis of macrocyclic peptides: the Trp-His-Gly-Arg derived macrocycle of moroidin
Harrison JR and Moody CJ
Tetrahedron Letters, 44(28), 5189-5191 (2003)
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Global Trade Item Number

SKUGTIN
PHL85778-10MG04061842665662
17308-1L04061838346513
17308-2.5L04061838118295