194557
Methoxyacetic acid
98%
Synonym(s):
NSC 7300
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About This Item
Linear Formula:
CH3OCH2COOH
CAS Number:
Molecular Weight:
90.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-894-6
Beilstein/REAXYS Number:
635800
MDL number:
Assay:
98%
Form:
liquid
Quality Level
assay
98%
form
liquid
refractive index
n20/D 1.417 (lit.)
bp
202-204 °C (lit.)
mp
7-9 °C (lit.)
density
1.174 g/mL at 25 °C (lit.)
functional group
carboxylic acid, ether
SMILES string
COCC(O)=O
InChI
1S/C3H6O3/c1-6-2-3(4)5/h2H2,1H3,(H,4,5)
InChI key
RMIODHQZRUFFFF-UHFFFAOYSA-N
General description
Methoxyacetic acid is the major metabolite of ester phthalates widely used in industry as gelling, viscosity and stabilizer reagents.
Application
Methoxyacetic acid was used in zebrafish embryotoxicity test to evaluate chemical toxicity after exposure of the complete vertebrate embryo during embryogenesis in ovo.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
237.2 °F - closed cup
flash_point_c
114 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Gargi Bagchi et al.
Reproductive biology and endocrinology : RB&E, 9, 42-42 (2011-04-02)
Optimal androgen signaling is critical for testicular development and spermatogenesis. Methoxyacetic acid (MAA), the primary active metabolite of the industrial chemical ethylene glycol monomethyl ether, disrupts spermatogenesis and causes testicular atrophy. Transcriptional trans-activation studies have indicated that MAA can enhance
Derek V Henley et al.
Environmental health perspectives, 117(11), 1702-1706 (2010-01-06)
Ethylene glycol monomethyl ether (EGME) exposure is associated with impaired reproductive function. The primary metabolite of EGME is methoxyacetic acid (MAA), a short-chain fatty acid that inhibits histone deacetylase activity and alters gene expression. Because estrogen signaling is necessary for
Gargi Bagchi et al.
Reproductive biology and endocrinology : RB&E, 8, 65-65 (2010-06-23)
Methoxyacetic acid (MAA) is the active metabolite of the widely used industrial chemical ethylene glycol monomethyl ether, which is associated with various developmental and reproductive toxicities, including neural toxicity, blood and immune disorders, limb degeneration and testicular toxicity. Testicular toxicity
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 194557-250G | 04061838346889 |
| 194557-50G | 04061838761309 |