Key Documents

View All Documentation

195650

2-Nitroimidazole

Name: 2-Nitroimidazole
Brand: ALDRICH

98%

Synonym(s):

Azomycin

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₃H₃N₃O₂

CAS Number:

527-73-1

Molecular Weight:

113.07

UNSPSC Code:

12352005

NACRES:

NA.22

PubChem Substance ID:

24851703

EC Number:

208-425-5

Beilstein/REAXYS Number:

116444

MDL number:

MFCD00005185

Assay:

98%

Form:

solid

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

200

assay

98%

form

solid

mp

287 °C (dec.) (lit.)

functional group

nitro

SMILES string

[O-][N+](=O)c1ncc[nH]1

InChI

1S/C3H3N3O2/c7-6(8)3-4-1-2-5-3/h1-2H,(H,4,5)

InChI key

YZEUHQHUFTYLPH-UHFFFAOYSA-N

Description

General description

2-Nitroimidazole is a natural antibiotic.

Application

2-Nitroimidazole was used in the synthesis of:

tert-butyl 2-(2-nitro-1H-imidazol-1-yl)ethylcarbamate
1-(2-(tert-butyldimethylsilyloxy)ethyl)-2-nitro-1H-imidazole
2-fluoro-N-(2-(2-nitro-1H-imidazol-1-yl)ethyl)acetamide
2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl 2-fluoroacetate
radiolabeling precursors - the bromo substituted analogs
nitroimidazole substituted boronic acids, precursors for imaging hypoxic tissue
potential site-selective radiosensitizers for estrogen receptor-rich tumors

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Analysis Note

solubility :
50 mg/mL in NH₄OH : soluble, clear, green-yellow, to very dark green-yellow to very dark yellow

hcodes

H302

pictograms

GHS07

signalword

Warning

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Nanoemulsions of sulfonamide carbonic anhydrase inhibitors strongly inhibit the growth of Trypanosoma cruzi.

Alane Beatriz Vermelho et al.

Journal of enzyme inhibition and medicinal chemistry, 33(1), 139-146 (2017-12-02)

Sulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitors targeting the α-class enzyme from the protozoan pathogen Trypanosoma cruzi, responsible of Chagas disease, were recently reported. Although many such derivatives showed low nanomolar activity in vitro, they were inefficient anti-T. cruzi agents

Aggregate Formation of Oligonucleotides that Assist Molecular Imaging for Tracking of the Oxygen Status in Tumor Tissue.

Kazuki Yoshihara et al.

Chembiochem : a European journal of chemical biology, 18(16), 1650-1658 (2017-05-16)

The use of DNA aggregates could be a promising strategy for the molecular imaging of biological functions. Herein, phosphorescent oligodeoxynucleotides were designed with the aim of visualizing oxygen fluctuation in tumor cells. DNA-ruthenium conjugates (DRCs) that consisted of oligodeoxynucleotides, a

J. Chem. Res. Synop., 92-92 (1993)

View All Related Papers

Global Trade Item Number

SKU	GTIN
195650-250MG	04061838761712
195650-1G	04061838761705