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Merck
CN

202371

Poly(ethylene glycol)

greener alternative

average Mn 300, hydroxyl

Synonym(s):

Polyethylene glycol, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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Product Name

Poly(ethylene glycol), average Mn 300

form

viscous liquid

mol wt

Mn 285-315, average Mn 300

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

refractive index

n20/D 1.463

pH

6-7 (23 °C, at 10 g/l)

viscosity

5.8 cSt(210 °F)(lit.)

mp

−15-−8 °C (lit.)

density

1.125 g/mL at 25 °C

Mw/Mn

1.1 (typical)

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks, PEG can have high water content, forming "hydrogels". Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. Polyethylene glycol (PEG) is an eco-friendly, biodegradable polymer widely used in pharmaceuticals and cosmetics. Its non-toxic nature and versatility make it a sustainable choice, derived from renewable resources, contributing to greener product formulations. Click here for more information.

Application


  • PEG modification increases thermostability and inhibitor resistance of Bst DNA polymerase.: This study demonstrates that polyethylene glycol (PEG) modification significantly enhances the thermostability and inhibitor resistance of Bst DNA polymerase, highlighting PEG′s potential in improving enzyme performance for biotechnological applications (Yang et al., 2024).

  • Development of Lyophilized Eukaryotic Cell-Free Protein Expression System Based on Leishmania tarentolae.: The incorporation of PEG in the lyophilization process of a cell-free protein expression system demonstrates its role in enhancing the stability and efficiency of biotechnological workflows (Alfaro-Palma et al., 2024).

  • A comprehensive review on singlet oxygen generation in nanomaterials and conjugated polymers for photodynamic therapy in the treatment of cancer.: This review highlights the application of PEGylated nanomaterials in photodynamic therapy, emphasizing its significance in improving biocompatibility and therapeutic efficacy in cancer treatments (Singh et al., 2024).




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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

428.0 °F - closed cup

flash_point_c

220.00 °C - closed cup

ppe

Eyeshields, Gloves



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Articles

The present publication focuses on synthesis and characterization of nanothick, chemically grafted polymer films (polymer brushes) on various inorganic and polymeric substrates.


Plasticizing collagen hydrolysate with glycerol and low-molecular weight poly(ethylene glycols)
Langmaier F, et al.
Thermochimica Acta, 469(1-2), 52-58 (2008)
Developing perylene diimide based acceptor polymers for organic photovoltaics
Liang Z, et al.
Synthetic Metals, 161(11-12), 1014-1021 (2011)
Rheological studies of disulfonated poly(arylene ether sulfone) plasticized with poly(ethylene glycol) for membrane formation
Oh HJ, et al.
Polymer, 55(6), 1574-1582 (2014)



Global Trade Item Number

SKUGTIN
202371-250G04061838764850
202371-500G04061838764867
202371-1KG04061838764843
202371-20KG04061838137999
202371-5G04061838764874