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Merck
CN

211281

9-Phenanthrol

technical grade

Synonym(s):

9-Hydroxyphenanthrene

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About This Item

Empirical Formula (Hill Notation):
C14H10O
CAS Number:
Molecular Weight:
194.23
UNSPSC Code:
12352100
EC Number:
207-602-4
MDL number:
NACRES:
NA.22
PubChem Substance ID:
Technical Service
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Quality Level

grade

technical grade

mp

139-143 °C (lit.)

SMILES string

Oc1cc2ccccc2c3ccccc13

InChI

1S/C14H10O/c15-14-9-10-5-1-2-6-11(10)12-7-3-4-8-13(12)14/h1-9,15H

InChI key

DZKIUEHLEXLYKM-UHFFFAOYSA-N

Application

9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes.

Biochem/physiol Actions

9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Alvaro Becerra et al.
Cardiovascular research, 91(4), 677-684 (2011-05-14)
Endothelial dysfunction is decisive in the progression of cardiovascular diseases. Lipopolysaccharide (LPS)-induced reactive oxygen species (ROS)-mediated endothelial cell death is a main feature observed in inflammation secondary to endotoxaemia, emerging as a leading cause of death among critically ill patients
Eric C Lin et al.
Frontiers in cellular neuroscience, 11, 182-182 (2017-07-18)
Temporal lobe epilepsy is characterized by recurrent seizures in one or both temporal lobes of the brain; some
R Guinamard et al.
British journal of pharmacology, 171(7), 1600-1613 (2014-01-18)
The phenanthrene-derivative 9-phenanthrol is a recently identified inhibitor of the transient receptor potential melastatin (TRPM) 4 channel, a Ca(2+) -activated non-selective cation channel whose mechanism of action remains to be determined. Subsequent studies performed on other ion channels confirm the



Global Trade Item Number

SKUGTIN
211281-1G04061838771711
211281-5G04061832279411