243086
Pyridine hydrochloride
98%
Synonym(s):
Pyridinium chloride
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About This Item
Empirical Formula (Hill Notation):
C5H5N · HCl
CAS Number:
Molecular Weight:
115.56
NACRES:
NA.22
PubChem Substance ID:
eCl@ss:
39151701
UNSPSC Code:
12352100
EC Number:
211-027-4
MDL number:
Beilstein/REAXYS Number:
3615340
Assay:
98%
Quality Level
assay
98%
bp
222-224 °C (lit.)
mp
145-147 °C (lit.)
solubility
ethanol: soluble 50 mg/mL, clear, colorless to light yellow
SMILES string
Cl[H].c1ccncc1
InChI
1S/C5H5N.ClH/c1-2-4-6-5-3-1;/h1-5H;1H
InChI key
AOJFQRQNPXYVLM-UHFFFAOYSA-N
General description
Pyridine hydrochloride is an acidic type demethylating agent used as a catalyst in deprotection of aromatic methyl ethers.
Application
Pyridine hydrochloride (pyridine hydrochloride) was used in the demethylation of 4,5-dimethyl-7-methoxy-1-tetralone.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Demethylation of methyl aryl ethers using pyridine hydrochloride in solvent-free conditions under microwave irradiation.
Kulkarni PP, et al.
J. Chem. Res. Synop., 6, 394-395 (1999)
Tatyana N Sevastyanova et al.
Molecular pharmacology, 86(5), 492-504 (2014-08-13)
Metabotropic glutamate receptors (mGluRs) function as dimers. Recent work suggests that mGluR1 and mGluR5 may physically interact, but the nature and functional consequences of this relationship have not been addressed. In this study, the functional and pharmacological consequences of this
Jipan Yu et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 19(13), 4271-4277 (2013-02-13)
Efficient copper-catalyzed aerobic oxidative C-H and C-C functionalization of 1-[2-(arylamino)aryl]ethanones leading to acridones has been developed. The procedure involves cleavage of aromatic C-H and acetyl C-C bonds with intramolecular formation of a diarylketone bond. The protocol uses inexpensive Cu(O2CCF3)2 as
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 653322-10G | 04061832732787 |
| 653322-25G | 04061832732794 |
| Y0000093 | 04061833794555 |
| 243086-100G | 04061825596013 |
| 243086-500G | 04061825596020 |
| 243086-5G | 04061825596037 |