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Merck
CN

246379

Azelaic acid

98%

Synonym(s):

Nonanedioic acid

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About This Item

Linear Formula:
HO2C(CH2)7CO2H
CAS Number:
Molecular Weight:
188.22
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
204-669-1
Beilstein/REAXYS Number:
1101094
MDL number:
Technical Service
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vapor density

6.5 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

assay

98%

form

powder

bp

286 °C/100 mmHg (lit.)

mp

109-111 °C (lit.)

SMILES string

OC(=O)CCCCCCCC(O)=O

InChI

1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)

InChI key

BDJRBEYXGGNYIS-UHFFFAOYSA-N

General description

Azelaic acid is an important monomer in the synthesis of various polymers. The presence of two carboxylic acid groups enables azelaic acid to act as a monomer for polycondensation reactions, leading to the formation of polyesters and other polymeric materials. Additionally, it is also used to prepare azelaic acid-based plasticizers to improve the mechanical properties of PVC, making them suitable for various applications, including films, coatings, and flexible products.

Application

Azelaic acid can be used:
  • As a bio-based monomer in the development of biodegradable polymers. These polymers are explored for a range of applications, including packaging materials, agricultural films, and other products where biodegradability is a key requirement.
  • As a crucial component in the synthesis of biodegradable copolyester plasticizers for PVC applications.
  • As a monomer in the synthesizing poly(glycerol azelaic acid) for tissue engineering applications. Its contributions to biocompatibility, mechanical properties, degradation behavior, and hydrophilicity make it an essential building block for developing advanced biomaterials aimed at enhancing tissue regeneration processes. In drug delivery systems, azelaic acid may play a role in the synthesis of polymers or other compounds used in drug delivery, potentially enhancing medication effectiveness through improved solubility or stability.
  • In skincare products.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

410.0 °F - closed cup

flash_point_c

210 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)



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Esther J van Zuuren et al.
Journal of the American Academy of Dermatology, 56(1), 107-115 (2006-12-28)
Rosacea is a common chronic skin and ocular condition. It is unclear which treatments are most effective. We have conducted a Cochrane review of rosacea therapies. This article is a distillation of that work. We sought to assess the evidence
Nicola Castellucci et al.
Amino acids, 41(3), 609-620 (2011-04-14)
A small library of stereoisomeric pseudopeptides able to make gels in different solvents has been prepared and their attitude to make gels in the presence of several metal ions was evaluated. Four benzyl esters and four carboxylic acids, all containing
Maria Zoeller et al.
Plant physiology, 160(1), 365-378 (2012-07-24)
Lipid peroxidation (LPO) is induced by a variety of abiotic and biotic stresses. Although LPO is involved in diverse signaling processes, little is known about the oxidation mechanisms and major lipid targets. A systematic lipidomics analysis of LPO in the



Global Trade Item Number

SKUGTIN
246379-100G04061825858852
246379-25G04061825858869