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Merck
CN

256226

N,N-Dimethyloctylamine

95%

Synonym(s):

1-(Dimethylamino)octane, N-Octyldimethylamine, Adma 8, DMOA

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About This Item

Linear Formula:
CH3(CH2)7N(CH3)2
CAS Number:
Molecular Weight:
157.30
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
230-939-3
Beilstein/REAXYS Number:
1698081
MDL number:
Assay:
95%
Form:
liquid
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vapor density

5.4 (vs air)

vapor pressure

0.8 mmHg ( 25 °C)

assay

95%

form

liquid

refractive index

n20/D 1.424 (lit.)

bp

195 °C (lit.)

mp

−57 °C (lit.)

density

0.765 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

CCCCCCCCN(C)C

InChI

1S/C10H23N/c1-4-5-6-7-8-9-10-11(2)3/h4-10H2,1-3H3

InChI key

UQKAOOAFEFCDGT-UHFFFAOYSA-N

Application

N,N-Dimethyloctylamine has been employed:
  • as ion-pairing agent in quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC
  • as counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography
  • as mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide in human plasma
  • in study of chiral separations by complexation with proteins in capillary zone electrophoresis


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Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

156.2 °F - closed cup

flash_point_c

69 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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J Hermansson et al.
Journal of pharmaceutical sciences, 71(2), 222-229 (1982-02-01)
Methods are presented for the separation of tetracycline, tetracycline analogs, and their potential impurities by reversed-phase ion-pair chromatography. The mobile phase consisted of a phosphate buffer with tripropylamine or N,N-dimethyloctylamine as counterions and acetonitrile as the organic modifier. The chromatographic
J Hermansson et al.
Journal of chromatography, 336(2), 321-328 (1984-12-12)
The direct resolution and quantitation of (R)- and (S)-disopyramide, isolated from human plasma, was accomplished using a chiral alpha 1-acid glycoprotein column. A LiChrosorb RP-2 column (50 X 3.0 mm I.D.) was used as a precolumn. Phosphate buffer, pH 6.20
E Smet et al.
Journal of pharmaceutical and biomedical analysis, 23(1), 175-183 (2000-07-18)
The phenothiazine derivative thiazinamium methylsulphate is a drug with antihistaminic and anticholinergic properties, often used in some types of obstructive lung diseases. Because there is a lack of chromatographic data available for its determination, the objective of the present investigation



Global Trade Item Number

SKUGTIN
256226-100ML04061836831899
256226-25ML04061836831905
256226-5ML04061826043455