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283215

Poly(allylamine hydrochloride)

average Mw ~17,500 (GPC vs. PEG std.)

Synonym(s):

PAA HCl, PAH

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About This Item

Linear Formula:
[CH2CH(CH2NH2 · HCl)]n
CAS Number:
71550-12-4
NACRES:
NA.23
PubChem Substance ID:
24857093
UNSPSC Code:
12162002
EC Number:
415-050-2
MDL number:
MFCD00084396
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form

solid

Quality Level

200

mol wt

average Mw ~17,500 (GPC vs. PEG std.)

SMILES string

Cl.NCC=C

InChI

1S/C3H7N/c1-2-3-4/h2H,1,3-4H2

InChI key

VVJKKWFAADXIJK-UHFFFAOYSA-N

General description

Poly(allylamine hydrochloride) (PAH) is a water-soluble weak-base and a biodegradable polymer.

Application

Poly(allylamine hydrochloride) can be used as a starting material to prepare:
  • Chitosan/PAH polymer blend films by solution casting technique. These films can be employed in injectable drug delivery systems and tissue generation.
  • Cross-linked amino-modified graphene oxide for the removal of Cr(IV) from aqueous solutions.
  • Polyelectrolyte multilayers(PEMs) by the layer-by-layer method. These PEMs can be used to prepare controlled drug delivery systems and coatings with controlled cell adhesion properties.
Used to make redox hydrogel-modified electrodes for measuring enzyme responses.

Features and Benefits

  • Excellent environmental stability
  • Water-soluble
  • Low cost

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ1651
MKCP9820
MKCP2299
MKCK8732
MKCN7553

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Articles

Layer-by-Layer (LbL) Assembly, A "Gentle Yet Flexible" Method Toward Functional Biomaterials

Recently, layer-by-layer (LbL) assembly has emerged as a versatile, gentle and, simple method for immobilization of functional molecules in an easily controllable thin film morphology.1,2 In this short review, we introduce recent advances in functional systems fabricated by using the mild, yet adaptable LbL technique.

Polyelectrolyte Multilayer Films and Membrane Functionalization

We present an article that discusses two applications in particular; first, using these layers as polyelectrolyte membranes to control permeability.

Jingguo Li et al.
Chemistry, an Asian journal, 8(2), 385-391 (2012-12-12)
Multimodal imaging and simultaneous therapy is highly desirable because it can provide complementary information from each imaging modality for accurate diagnosis and, at the same time, afford an imaging-guided focused tumor therapy. In this study, indocyanine green (ICG), a near-infrared
Ya Wang et al.
Macromolecular bioscience, 12(10), 1321-1325 (2012-09-12)
Fluorescent-magnetic-biotargeting multifunctional microcapsules (FMBMMs) are designed and fabricated via layer-by-layer assembly. It is found that the arginine-glycine-aspartate-modified FMBMMs were capable of sensitively detecting and efficiently isolating approximately 80% target cancer cells within 20 min. More importantly, FMBMMs present a general
Bing Wang et al.
Macromolecular bioscience, 12(11), 1534-1545 (2012-09-26)
The mechanism of the cellular uptake of polyelectrolyte microcapsules and its influences on the functions and toxicity of human SMCs are explored. The covalently assembled poly(allylamine hydrochloride)/glutaraldehyde microcapsules are easily ingested by SMCs mainly through macropinosis and caveolae-mediated endocytosis pathways.
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Global Trade Item Number

SKUGTIN
283215-25G04061826236871
283215-5G04061826236888