288144
Tricarbonyldichlororuthenium(II) dimer
Synonym(s):
CORM-2
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
[Ru(CO)3Cl2]2
CAS Number:
Molecular Weight:
512.01
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12161600
MDL number:
Quality Level
reaction suitability
core: ruthenium, reagent type: catalyst
SMILES string
[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].[C-]#[O+].Cl[Ru]Cl.Cl[Ru]Cl
InChI
1S/6CO.4ClH.2Ru/c6*1-2;;;;;;/h;;;;;;4*1H;;/q;;;;;;;;;;2*+2/p-4
InChI key
JYHHJVKGDCZCCL-UHFFFAOYSA-J
Application
Tricarbonyldichlororuthenium(II) dimer can be used in the deuteration reaction for labeling secondary amines. It can also be used for the synthesis of racemization catalysts by reacting with cyclopenta[l]phenanthrenyl and cyclopenta[a]acenaphthylenyl ligands.
Carbon monoxide-releasing molecule used for pharamological studies including:
Used as a CO donor for reactive oxygen species mediated bacterial killing
- Enhancement of coagulation and attenuation of vulnerability to fibrinolysis
- Investigations of P2X4 as a possible target
- Possible modification of thrombus growth or disintegration
- Enhances fibrinogen as a substrate for thrombin
- Regulation of ion transport by gasotransmitters
Used as a CO donor for reactive oxygen species mediated bacterial killing
signalword
Warning
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
V G Nielsen et al.
Human & experimental toxicology, 36(7), 727-733 (2016-08-05)
Hypofibrinogenemia is an important clinical consequence following envenomation by Lachesis muta muta, usually attenuated or prevented by administration of antivenom. The venom of L. m. muta contains both a metalloproteinase fibrinogenase and a serine protease thrombin-like enzyme, and exposure of
Po-Min Yang et al.
Vascular pharmacology, 87, 209-218 (2016-10-11)
The production of nitric oxide (NO) by endothelial NO synthase (eNOS) plays a major role in maintaining vascular homeostasis. This study elucidated the potential role of carbon monoxide (CO)-releasing molecules (CORMs) in NO production and explored the underlying mechanisms in
Vance G Nielsen et al.
Basic & clinical pharmacology & toxicology, 120(2), 207-212 (2016-08-23)
Since the introduction of antivenom administration over a century ago to treat venomous snake bite, it has been the most effective therapy for saving life and limb. However, this treatment is not always effective and not without potential life-threatening side
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 288144-500MG | 04061826273418 |