Key Documents

View All Documentation

308560

4-Amino-6-chloro-1,3-benzenedisulfonamide

Name: 4-Amino-6-chloro-1,3-benzenedisulfonamide
Brand: ALDRICH

98%

Synonym(s):

3-Chloroaniline-4,6-disulfonamide, 4-Amino-6-chlorobenzene-1,3-disulfonamide

Select a Size

Change View

About This Item

Linear Formula:

H₂NC₆H₂(Cl)(SO₂NH₂)₂

CAS Number:

121-30-2

Molecular Weight:

285.73

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24858677

EC Number:

204-463-1

Beilstein/REAXYS Number:

1083877

MDL number:

MFCD00007933

Assay:

98%

Form:

powder

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

assay

98%

form

powder

mp

257-261 °C (lit.)

functional group

chloro

SMILES string

Nc1cc(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O

InChI

1S/C6H8ClN3O4S2/c7-3-1-4(8)6(16(10,13)14)2-5(3)15(9,11)12/h1-2H,8H2,(H2,9,11,12)(H2,10,13,14)

InChI key

IHJCXVZDYSXXFT-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760), CA5A(763), CA5B(11238), CA9(768)

Description

General description

4-Amino-6-chloro-1,3-benzenedisulfonamide is a potent inhibitor of gastric pathogen, Helicobacter pylori (hpCA).

Application

4-Amino-6-chloro-1,3-benzenedisulfonamide was used in the synthesis of deuterated thiazides by undergoing condensation with appropriately labeled aldehydes.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mass spectrometric behavior of thiazide-based diuretics after electrospray ionization and collision-induced dissociation.

Mario Thevis et al.

Analytical chemistry, 74(15), 3802-3808 (2002-08-15)

The mass spectrometric behavior of 21 thiazide-based compounds after electrospray ionization in the negative ion mode and collision-induced dissociation was investigated on a triple-stage quadrupole mass spectrometer. The mass spectra show individual and common fragmentation patterns, the generations of which

Validated micellar electrokinetic capillary chromatography method for quality control of the drug substances hydrochlorothiazide and chlorothiazide.

B R Thomas et al.

Journal of chromatography. B, Biomedical applications, 657(2), 383-394 (1994-07-15)

A stability-indicating, quality control analysis method was developed and validated for the diuretic drug substances hydrochlorothiazide (HCTZ) and chlorothiazide (CTZ). Micellar electrokinetic capillary chromatography employing the anionic detergent sodium dodecyl sulfate at 30 mM in 20 mM sodium borate buffer

Biopharmaceutical studies of thiazide diuretics. III. In vivo formation of 2-amino-4-chloro-m-benzenedisulfonamide as a metabolite of hydrochlorothiazide in a patient.

T Okuda et al.

Chemical & pharmaceutical bulletin, 35(8), 3516-3518 (1987-08-01)

View All Related Papers

Global Trade Item Number

SKU	GTIN
308560-5G	04061826674840
308560-100G	04061826674826