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411027

Piperidine

Name: Piperidine
Brand: ALDRICH

≥99.5%, purified by redistillation

Synonym(s):

Hexahydropyridine

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About This Item

Empirical Formula (Hill Notation):

C₅H₁₁N

CAS Number:

110-89-4

Molecular Weight:

85.15

UNSPSC Code:

12352005

NACRES:

NA.22

PubChem Substance ID:

24865722

EC Number:

203-813-0

Beilstein/REAXYS Number:

102438

MDL number:

MFCD00005979

Assay:

≥99.5%

Bp:

106 °C (lit.)

Vapor pressure:

23 mmHg ( 20 °C)

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Properties

vapor density

3 (vs air)

Quality Level

200

vapor pressure

23 mmHg ( 20 °C)

assay

≥99.5%

form

liquid

purified by

redistillation

refractive index

n20/D 1.452 (lit.)

bp

106 °C (lit.)

mp

−13 °C (lit.)

density

0.862 g/mL at 20 °C (lit.)

SMILES string

C1CCNCC1

InChI

1S/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H2

InChI key

NQRYJNQNLNOLGT-UHFFFAOYSA-N

Description

Application

Piperidine may be used as a base for the oxidative homocoupling of terminal alkynes to form symmetrical 1,4-disubstituted 1,3-diynes in the presence of copper nanoparticle on polyaniline support catalyst. It may also be used for cleaving the Fmoc-group in N^α-9-fluorenylmethyloxycarbonyl (Fmoc) amino acids.

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pictograms

GHS02,GHS06,GHS05

signalword

Danger

hcodes

H225,H302,H311 + H331,H314

pcodes

P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

60.8 °F - closed cup

flash_point_c

16 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

易制毒化学品（2类）

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Polymer-Supported Cu?Nanoparticle as an Efficient and Recyclable Catalyst for Oxidative Homocoupling of Terminal Alkynes.

Aziz ST

Catalysis Letters, 148(1), 205-213 (2018)

Solid?phase peptide synthesis using mild base cleavage of N?-fluorenylmethyloxycarbonylamino acids, exemplified by a synthesis of dihydrosomatostatin.

Chang CD

Chemical Biology & Drug Design, 11(3), 246-249 (1978)

Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.

Xuwang Chen et al.

Bioorganic & medicinal chemistry, 20(12), 3856-3864 (2012-05-18)

A novel series of piperidine-linked amino-triazine derivatives were designed, synthesized and evaluated for in vitro anti-HIV activity as non-nucleoside reverse transcriptase inhibitors on the basis of our previous work. Screening results indicated that most compounds showed excellent activity against wild-type

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Global Trade Item Number

SKU	GTIN
411027-1L	04061832019772
411027-100ML	04061832019765