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417963

Chitosan

Name: Chitosan
Brand: ALDRICH

from shrimp shells, practical grade

Synonym(s):

Deacetylated chitin, Poly(D-glucosamine), Chitosan & derivatives

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About This Item

CAS Number:

9012-76-4

UNSPSC Code:

12352201

NACRES:

NA.23

MDL number:

MFCD00161512

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Properties

biological source

shrimp shells

Quality Level

200

grade

practical grade

form

solid

mol wt

190000-375000 Da

viscosity

>200 cP, 1 wt. % in 1% acetic acid(20 °C, Brookfield)(lit.)

solubility

1 M acetic acid: 10 mg/mL

SMILES string

N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5N)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6N)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7N)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8N)O)O[C@@H]9O[C@@H]([C@H](

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI key

FLASNYPZGWUPSU-SICDJOISSA-N

Description

Application

Forms gels with multivalent anions. Gives clear solutions that dry to strong, clear films.

Features and Benefits

Biocompatible, antibacterial and environmentally friendly polyelectrolyte with a variety of applications including water treatment, chromatography, additives for cosmetics, textile treatment for antimicrobial activity, novel fibers for textiles, photographic papers, biodegradable films, biomedical devices, and microcapsule implants for controlled release in drug delivery.

Biocompatible, antibacterial and environmentally friendly polyelectrolyte.

Physical form

≥ 75% deacetylated

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Storage Class

11 - Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Articles

Chitosan in Pharmaceutical Applications

Polymers, natural or synthetic, are vital in medical advancements, contributing to device and pharmaceutical development in therapy.

Preparation of Chitosan Microparticles by Spray Drying

Carcinogenic compounds in elastomers: 1,3-butadiene and isoprene used in elastomer manufacturing, classified as carcinogenic by IARC.

Chitosan-based Biomaterials

Chitin, a natural polysaccharide, is the second most abundant natural biopolymer in the world, after cellulose.

Hierarchical microchannel architecture in chitosan/bioactive glass scaffolds via electrophoretic deposition positive-replica.

Arash Ghalayani Esfahani et al.

Journal of biomedical materials research. Part A, 107(7), 1455-1465 (2019-02-21)

One of the main challenges in the design of scaffolds for cortical bone regeneration is mimicking the highly oriented, hierarchical structure of the native tissue in an efficient, simple, and consistent way. As a possible solution to this challenge, positive

Chitosan stabilizes platelet growth factors and modulates stem cell differentiation toward tissue regeneration.

Alberto Busilacchi et al.

Carbohydrate polymers, 98(1), 665-676 (2013-08-31)

The idea of using chitosan as a functional delivery aid to support simultaneously PRP, stem cells and growth factors (GF) is associated with the intention to use morphogenic biomaterials to modulate the natural healing sequence in bone and other tissues.

Thermosensitive chitosan/glycerophosphate-based hydrogel and its derivatives in pharmaceutical and biomedical applications.

Stephanie Supper et al.

Expert opinion on drug delivery, 11(2), 249-267 (2013-12-07)

Thermogelling chitosan (CS)/glycerophosphate (GP) solutions have been reported as a new type of parenteral in situ forming depot system. These free-flowing solutions at ambient temperature turn into semi-solid hydrogels after parenteral administration. Formulation parameters such as CS physico-chemical characteristics, CS/gelling

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Global Trade Item Number

SKU	GTIN
417963-100G	04061832090580
417963-25G	04061832090641