435007
Hydroxypropyl cellulose
average Mw ~80,000, powder, 20 mesh particle size (99% through)
Synonym(s):
HPC, Cellulose & cellulose derivatives
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About This Item
description
biological oxygen demand (BOD) 14,000 ppm
Quality Level
form
powder
autoignition temp.
752 °F
mol wt
average Mw ~80,000
impurities
<5 wt. %
particle size
20 mesh (99% through)
pH
5.0-8.5
interfacial tension mineral oil
12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)
viscosity
250-800 cP, 10 wt. % in H2O(25 °C)(lit.)
solubility
H2O: insoluble (above 45 °C), polar organic solvents: soluble
density
0.5 g/mL at 25 °C (lit.)
SMILES string
N(C)(C)c1cc(c(cc1)C(N)CC)C
InChI
1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3
InChI key
RRHXDYJWVYFMKV-UHFFFAOYSA-N
General description
Hydroxypropyl cellulose (HPC) is biocompatible in nature and exhibits low critical solution temperature (LCST). It has been reported to be prepared by reacting cellulose with alkali, producing alkali cellulose which is consecutively reacted with propylene oxide. HPC is soluble in water at lower than RT. Viscosity behaves inversely to rise in temperature.
Application
Copolymers composed of HPC backbones with poly((2-dimethyl amino)ethyl methacrylate side chains has been synthesized for gene delivery. HPC has been used as a binder in to nanostructured anatase membranes. Polymer conjugates made of HPC backbones and poly(N-isopropylacryamide) as side chains act as smart hydrogels. HPC has been reported to be studied as a glue.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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F J Xu et al.
Bioconjugate chemistry, 20(8), 1449-1458 (2009-08-04)
Cationic polymers have been of interest and importance as nonviral gene delivery carriers. Herein, well-defined comb-shaped cationic copolymers (HPDs) composed of long biocompatible hydroxypropyl cellulose (or HPC) backbones and short poly((2-dimethyl amino)ethyl methacrylate) (or P(DMAEMA)) side chains were prepared as
Thomas E. Furia
CRC Handbook of Food Additives null
F J Xu et al.
Bioconjugate chemistry, 21(3), 456-464 (2010-02-25)
Hydroxypropyl cellulose (HPC) possesses a lower critical solution temperature (LCST) above 40 °C, while the poly(N-isopropylacrylamide) (P(NIPAAm)) exhibits a LCST of about 32 °C. Herein, comb-shaped copolymer conjugates of HPC backbones and low-molecular-weight P(NIPAAm) side chains (HPC-g-P(NIPAAm) or HPN) were
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 435007-100G | 04061838111234 |
| 435007-250G | 04061832113135 |
| 435007-5G | 04061838054135 |