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Merck
CN

457647

Poly(D,L-lactide-co-caprolactone)

DL-lactide 86 mol %

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About This Item

UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
MDL number:
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form

solid

feed ratio

lactide:caprolactone 85:15

composition

DL-lactide, 86 mol %

inherent viscosity

0.7-0.9 dL/g, in chloroform(lit.)

transition temp

Tg 16 °C

storage temp.

2-8°C

SMILES string

CC(O)C(O)=O.OCCCCC(O)=O

InChI

1S/C5H10O3.C3H6O3/c6-4-2-1-3-5(7)8;1-2(4)3(5)6/h6H,1-4H2,(H,7,8);2,4H,1H3,(H,5,6)

InChI key

LLHKFIFJPCHEOM-UHFFFAOYSA-N

Application

Poly(DL-lactide-co-caprolactone) (PLA-PCL) is a biodegradable block copolymer that may be used as monofilament sutures and nanoparticle-based drug delivery systems.

Features and Benefits

Biocompatible, biodegradable polymer.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Articles

In the past two decades, tissue engineering and regenerative medicine have become important interdisciplinary fields that span biology, chemistry, engineering, and medicine.

Innovations in polymer technology have had a significant impact on the advancement of novel drug delivery systems.


Polymeric scaffolds in tissue engineering application: a review.
Dhandayuthapani B, et al.
International Journal of Polymer Science (2011)
Novel docetaxel-loaded nanoparticles based on poly (lactide-co-caprolactone) and poly (lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies.
Sanna V, et al.
Nanoscale Research Letters, 6(1), 260-260 (2011)



Global Trade Item Number

SKUGTIN
457647-5G04061832342344