47618
Fmoc-Asp(OtBu)-OH
≥98.0% (HPLC), for peptide synthesis
Synonym(s):
Fmoc-L-aspartic acid 4-tert-butyl ester
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About This Item
Empirical Formula (Hill Notation):
C23H25NO6
CAS Number:
Molecular Weight:
411.45
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
276-251-7
MDL number:
Beilstein/REAXYS Number:
3635671
Product Name
Fmoc-Asp(OtBu)-OH, ≥98.0% (HPLC)
Quality Level
assay
≥98.0% (HPLC)
form
powder
optical activity
[α]20/D −24±2°, c = 1% in DMF
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
mp
148-150 °C (dec.)
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
SMILES string
CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI
1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
InChI key
FODJWPHPWBKDON-IBGZPJMESA-N
General description
Fmoc-Asp(OtBu)-OH also known as Fmoc-L-aspartic acid 4-tert-butyl ester, is a Fmoc protected amino acid, used in solid phase peptide synthesis.
Application
Fmoc-Asp(OtBu)-OH is used to prevent the formation of aspartimide by-products in Fmoc solid phase peptide synthesis.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Fengyang Xu et al.
ACS applied materials & interfaces, 8(44), 29906-29914 (2016-10-21)
In this work, we reported the generation of a novel supramolecular hydrogelator from a peptide derivative which consisted of a structural motif (e.g., Fc-FF) for supramolecular self-assembly and a functional moiety (e.g., RGD) for integrin binding. Following self-assembly in water
Jisi Zhao et al.
Molecules (Basel, Switzerland), 24(4) (2019-03-03)
Photodynamic therapy (PDT) is an established therapeutic modality for the management of cancers. Conjugation with tumor-specific small molecule ligands (e.g., short peptides or peptidomimetics) could increase the tumor targeting of PDT agents, which is very important for improving the outcome
R Ashton Lavoie et al.
International journal of molecular sciences, 20(7) (2019-04-11)
The growing integration of quality-by-design (QbD) concepts in biomanufacturing calls for a detailed and quantitative knowledge of the profile of impurities and their impact on the product safety and efficacy. Particularly valuable is the determination of the residual level of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| CDS004725-100MG | 04061828955503 |
| 47618-1G-F | 04061826222638 |
| 47618-1KG-F | 04061826222645 |
| 47618-100G-F | 04061832362106 |
| 47618-10G-F | 04061832362113 |
| 47618-25G-F | 04061832362120 |