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Merck
CN

493813

Morpholine, polymer-bound

200-400 mesh, extent of labeling: 2.75-3.25 mmol/g loading, 1 % cross-linked

Synonym(s):

N-Vinylbenzylmorpholine-divinylbenzene copolymer

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About This Item

Empirical Formula (Hill Notation):
C29H33NO
CAS Number:
Molecular Weight:
411.58
UNSPSC Code:
12352128
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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Quality Level

crosslinking

1 % cross-linked

reaction suitability

reaction type: solution phase peptide synthesis, reactivity: proton reactive

extent of labeling

2.75-3.25 mmol/g loading

particle size

200-400 mesh

SMILES string

N1CCOCC1

InChI

1S/C4H9NO/c1-3-6-4-2-5-1/h5H,1-4H2

InChI key

YNAVUWVOSKDBBP-UHFFFAOYSA-N

Application

This polymer-bound tertiary amine is used as a base in the synthesis of sulfonamides and amides, serves as a catalyst in the functionalization of secondary amines, with acid chlorides. The resin was also used as a polymer-bound base to scavenge excess acid.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Blackburn, C. et al.
Tetrahedron Letters, 39, 3635-3635 (1998)
Creswell, M.W., et al.
Tetrahedron, 54, 3983-3983 (1998)
R.J. Booth et al.
Journal of the American Chemical Society, 119, 4882-4882 (1997)



Global Trade Item Number

SKUGTIN
493813-25G04061833547885