49960
1-Oleoyl-rac-glycerol
technical, ~40% (TLC)
Synonym(s):
1-(cis-9-Octadecenoyl)-rac-glycerol, rac-Glycerol 1-monooleate, DL-α-Monoolein, Glyceryl cis-9-octadecenoate, Monoolein
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About This Item
Linear Formula:
CH3(CH2)7CH=CH(CH2)7COOCH2CHOHCH2OH
CAS Number:
Molecular Weight:
356.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-827-7
Beilstein/REAXYS Number:
1728976
MDL number:
description
non-ionic
Quality Level
grade
technical
concentration
~40% (TLC)
impurities
15-40% diglyceride, 15-40% triglyceride
functional group
ester, hydroxyl
SMILES string
O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
InChI
1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChI key
RZRNAYUHWVFMIP-KTKRTIGZSA-N
General description
1-Oleoyl-rac-glycerol is commonly known as monoolein (MO). It is an amphiphilic molecule that is made up of a glycerol backbone and a hydrocarbon chain.
Application
- Bovine Serum Albumin (BSA) Encapsulated in DODAB: MO (1: 2) Liposomes for Targeted Drug Delivery: Development and Characterization: This study focuses on developing liposomes consisting of Dioctadecyldimethylammonium Bromide (DODAB) and 1-oleoyl-rac-glycerol for targeted drug delivery (A VAN DIJCK, 2014).
- An Innovative Nanocarrier for Neuroprotection: Investigates the therapeutic benefits of encapsulating curcumin in stealth nanocarriers of DODAB and 1-oleoyl-rac-glycerol (MO) (1: 2) (T Soares, No Date Provided).
- Supporting Information Light-responsive Molecular Release from Cubosomes using Swell-Squeeze Lattice Control: Discusses molecular release mechanisms in structures containing 1-oleoyl-rac-glycerol (BE Jones et al., No Date Provided).
- The Potential of Macroporous Silica—Nanocrystalline Cellulose Combination for Formulating Dry Emulsion Systems with Improved Flow Properties: A DoE Study: Details the formulation of dry emulsion systems incorporating 1-oleoyl-rac-glycerol for improved pharmaceutical applications (M Pohlen, L Pirker, R Dreu, 2021).
- The Metabolomic Bioenergetic Signature of Opa1-Disrupted Mouse Embryonic Fibroblasts Highlights Aspartate Deficiency: Includes an analysis of metabolic changes, noting the role of 1-oleoyl-rac-glycerol among other compounds (C Bocca et al., 2018).
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Storage Class
10 - Combustible liquids
flash_point_f
309.2 °F - closed cup
flash_point_c
154.0 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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Nicholas J Wright et al.
Nature structural & molecular biology, 26(7), 599-606 (2019-06-27)
The human equilibrative nucleoside transporter 1 (hENT1), a member of the SLC29 family, plays crucial roles in adenosine signaling, cellular uptake of nucleoside for DNA and RNA synthesis, and nucleoside-derived anticancer and antiviral drug transport in humans. Because of its
Mona Basha et al.
International journal of pharmaceutics, 532(1), 478-490 (2017-09-20)
The current article highlights the application of spray drying technique to produce an ultra-fine powder encapsulating the antihyperlipidemic drug, atorvastatin calcium (ATV). First, ATV was dissolved in an emulsion formulation, and different carriers (pectin, alginate, chitosan HCl and hydroxypropylmethyl cellulose)
Monoolein: a magic lipid?
Kulkarni CV, et al.
Physical Chemistry Chemical Physics, 13(8), 3004-3021 (2011)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 49960-1KG | 04061832422046 |
| 49960-10ML-KC | 04061837332579 |
| 49960-250G | 04061832422053 |