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572667

Baicalin

Name: Baicalin
Brand: ALDRICH

95%

Synonym(s):

5,6-Dihydroxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid, Baicalein 7-O-β-D-glucuronide

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₁₈O₁₁

CAS Number:

21967-41-9

Molecular Weight:

446.36

NACRES:

NA.22

PubChem Substance ID:

24880654

UNSPSC Code:

12352201

MDL number:

MFCD00134418

Assay:

95%

Form:

solid

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Properties

Quality Level

100

assay

95%

form

solid

optical activity

[α]20/D −85°, c = 1 in DMSO

mp

202-205 °C (dec.) (lit.)

functional group

carboxylic acid, ether, hydroxyl, ketone, phenyl

SMILES string

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccccc4

InChI

1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1

InChI key

IKIIZLYTISPENI-ZFORQUDYSA-N

Gene Information

mouse ... Hexa(15211)

Description

General description

Baicalin is a key flavonoid found in the roots of Scutellaria baicalensis. It is known to have different biological activities, such as anti-oxidative, anti-inflammatory, antitumor and anti-apoptotic activities.

Application

Baicalin has been used in a study to examine its neuroprotective effect in chronically stressed rats.2

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Baicalin influences the dendritic morphology of newborn neurons in the hippocampus of chronically stressed rats.

Jiang X, et al.

Neural Regeneration Research, 8(6), 496-496 (2013)

Baicalin Attenuates Hypoxia-Induced Pulmonary Arterial Hypertension to Improve Hypoxic Cor Pulmonale by Reducing the Activity of the p38 MAPK Signaling Pathway and MMP-9.

Yan S, et al.

Evidence-Based Complementary and Alternative Medicine : ECAM, 2016 (2016)

D-Alpha-tocopherol acid polyethylene glycol 1000 succinate, an effective stabilizer during solidification transformation of baicalin nanosuspensions.

Peng-Fei Yue et al.

International journal of pharmaceutics, 443(1-2), 279-287 (2013-01-08)

Baicalin nanosuspensions, stabilized with 10% TPGS (relative to the weight of baicalin), were transformed into nanosuspensions powders by solidification process. Solidification methods for this transformation included freeze-drying, spray drying or vacuum drying. High pressure homogenization was applied for production of

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Global Trade Item Number

SKU	GTIN
572667-1G	04061832620848