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61745

N-Lauroylsarcosine sodium salt

≥97.0% (HPLC)

Synonym(s):

N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
137-16-6
Molecular Weight:
293.38
UNSPSC Code:
12161902
NACRES:
NA.22
PubChem Substance ID:
57651863
EC Number:
205-281-5
Beilstein/REAXYS Number:
5322974
MDL number:
MFCD00042728
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description

anionic

Quality Level

200

assay

≥97.0% (HPLC)

form

powder

mol wt

micellar avg mol wt 600

aggregation number

2

technique(s)

protein expression: suitable, protein purification: suitable, protein quantification: suitable

impurities

≤7% water

CMC

14.6 mM (20-25°C)

solubility

H2O: very soluble 293 g/L at 20 °C

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

General description

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

Application

N-Lauroylsarcosine sodium salt has been used to study the complexing ability of a novel amphiphilic γ-cyclodextrin with anionic surfactants.

Other Notes

Anionic surfactant.

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pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

512.6 °F - closed cup

flash_point_c

267 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG4870
BCCG4113
BCCD3171
BCCD3170
BCCC7389

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A facile one-pot synthesis of novel amphiphilic perfluoroalkyl ester functionalized ?-cyclodextrin and complex formation with anionic surfactants.
Lim KT
Journal of Fluorine Chemistry, 127(6), 730-735 (2006)
Jocelyne Piret et al.
Antimicrobial agents and chemotherapy, 46(9), 2933-2942 (2002-08-17)
The mechanisms of herpes simplex virus (HSV) inactivation by sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), two anionic surfactants with protein denaturant potency, have been evaluated in cultured cells. Results showed that pretreatment of HSV type 1 (HSV-1) strain F
S Roy et al.
Antimicrobial agents and chemotherapy, 45(6), 1671-1681 (2001-05-17)
The microbicidal efficacies of two anionic surfactants, sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), were evaluated in cultured cells and in a murine model of herpes simplex type 2 (HSV-2) intravaginal infection. In vitro studies showed that SLS and LS
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Global Trade Item Number

SKUGTIN
61745-250G04061835555345
61745-1KG04061832700625
61745-50G04061832595283