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Merck
CN

700312

Iron oxide(II,III), magnetic nanoparticles solution

10 nm avg. part. size, 5 mg/mL in toluene

Synonym(s):

Magnetic iron oxide nanocrystals, Magnetite, Superparamagnetic iron oxide nanoparticles

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About This Item

Empirical Formula (Hill Notation):
Fe3O4
CAS Number:
Molecular Weight:
231.53
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
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Quality Level

form

nanoparticles, solution

concentration

5 mg/mL in toluene

magnetization

>45 emu/g (at ambient temperature under 4500 Oe)

avg. part. size

10 nm

particle size

9-11 nm (TEM; conforms)

density

0.865 g/mL at 25 °C

SMILES string

O=[Fe].O=[Fe]O[Fe]=O

InChI

1S/3Fe.4O

InChI key

SZVJSHCCFOBDDC-UHFFFAOYSA-N

General description

Iron oxide(II,III), magnetic nanoparticles solution (Fe3O4) is an organic solvent dispersed nanoparticle solution, which can be synthesized by the thermal decomposition of iron acetylacetonate in 2-pyrrolidone. It is majorly used in biomedical applications due to its magnetic properties, particle size, and surface properties.
It contains <1.0% oleic acid stabilizing ligands.
Concentration 5mg/ml includes total weight nanocrystals plus ligands.

Application

Fe3O4 can be used in the targeting and imaging of tumor cells for cancer therapy-based applications. It may also be used in the separation of tumor cells from fresh whole blood. It can also be used as an effective material in drug delivery systems and magnetic resonance imaging (MRI).


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Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

target_organs

Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

45.0 °F

flash_point_c

7.2 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

易制毒化学品(3类)
危险化学品

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Articles

Prof. Yadong Yin discusses various synthesis methods of magnetite nanocrystals and their applications in different fields.

Professor Hui Mao explores the use of superparamagnetic iron oxide nanoparticles (INOPs) that offer an alternate contrast-enhancing mechanism.

Graphene is a unique two-dimensional (2D) structure of monolayer carbon atoms packed into a dense honeycomb crystal that has attracted great interest due to its diverse and fascinating properties.

View All Articles

Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood
Xu H, et al.
Biomaterials, 32(36), 9758-9765 (2011)
Nonpolymeric coatings of iron oxide colloids for biological use as magnetic resonance imaging contrast agents
Portet D, et al.
Journal of Colloid and Interface Science, 238(1), 37-42 (2001)
Targeted magnetic iron oxide nanoparticles for tumor imaging and therapy
Peng X, et al.
International journal of nanomedicine, 3(3), 311-311 (2008)



Global Trade Item Number

SKUGTIN
700312-5ML04061832795485