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Merck
CN

73861

N-Nitrosodiethylamine

≥99.0% (GC)

Synonym(s):

Diethylnitrosamine

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About This Item

Linear Formula:
(C2H5)2NNO
CAS Number:
Molecular Weight:
102.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-226-1
Beilstein/REAXYS Number:
1744991
MDL number:
Assay:
≥99.0% (GC)
Form:
liquid
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Quality Level

assay

≥99.0% (GC)

form

liquid

IVD

for in vitro diagnostic use

bp

177 °C (lit.)

density

0.95 g/mL (lit.)

functional group

N-nitroso, amine, nitroso

SMILES string

CCN(CC)N=O

InChI

1S/C4H10N2O/c1-3-6(4-2)5-7/h3-4H2,1-2H3

InChI key

WBNQDOYYEUMPFS-UHFFFAOYSA-N

Application

N-Nitrosodiethylamine can be used as a reactant to synthesize:
  • α-Amino oxime derivatives from alkenes via visible-light-induced photoaddition in the presence of HCl.
  • Diethylnitrosamine metalloporphyrin complexes from metalloporphyrins in the presence of dichloromethane.
N-Nitrosodiethylamine can also be used in the synthesis of 1,1-diethylhydrazine.


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 3 - Carc. 1B

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Changyu Zhu et al.
Journal of hepatology, 74(3), 613-626 (2020-10-11)
The hepatocyte Notch pathway is a pathogenic factor in non-alcoholic steatohepatitis (NASH)-associated fibrosis, but its role in hepatocellular carcinoma (HCC) is less well defined. Herein, we aimed to characterize the molecular and clinical features of Notch-active human HCC, and to
Pro-Resolving Lipid Mediator Resolvin E1 Mitigates the Progress of Diethylnitrosamine-Induced Liver Fibrosis in Sprague-Dawley Rats by Attenuating Fibrogenesis and Restricting Proliferation.
Rodriguez, et al.
International Journal of Molecular Sciences, 21 (2021)
Veeraperumal Suresh et al.
Carbohydrate polymers, 92(2), 1377-1385 (2013-02-13)
Crude fucoidan from Sargassum plagiophyllum extracted from blade and purified by Q-Sepharose fast flow anion-exchange chromatography and three fucoidan fractions were obtained. Maximum sulphate containing fucoidan fraction was considered as purified fucoidan and purity was checked with agarose gel electrophoresis.



Global Trade Item Number

SKUGTIN
73861-10ML04061832883830