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About This Item
Empirical Formula (Hill Notation):
C10H17BF4N4O3
Molecular Weight:
328.07
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:
Assay:
97%
Form:
solid
Quality Level
assay
97%
form
solid
mp
202-207 °C
functional group
ether
SMILES string
F[B-](F)(F)F.COc1nc(OC)nc(n1)[N+]2(C)CCOCC2
InChI
1S/C10H17N4O3.BF4/c1-14(4-6-17-7-5-14)8-11-9(15-2)13-10(12-8)16-3;2-1(3,4)5/h4-7H2,1-3H3;/q+1;-1
InChI key
LCRXDNPNQMIQFZ-UHFFFAOYSA-N
Application
4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium tetrafluoroborate (DMTMM BF4) can be used as a coupling reagent alternative to DMTMM Cl in peptide synthesis because of its stability. It is also used in the synthesis of:
- Esters and peptides in both solution and solid-phase.
- γ-aminobutyric acid (GABA)-containing cyclic heptapeptide, unguisin A.
- The cyclization of linear tetrapeptides.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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George Lo Huang et al.
Nanomaterials (Basel, Switzerland), 9(5) (2019-05-12)
Indoleamine 2,3-dioxygenase (IDO) is an immunomodulating enzyme that is overexpressed in many cancers with poor prognosis. IDO suppresses T cell immunity by catabolizing tryptophan into kynurenine (KYN), which induces apoptosis in T effector cells and enhances T regulatory cells, providing
Xiaoqin Zhang et al.
Carbohydrate polymers, 247, 116749-116749 (2020-08-25)
To enhance the drug delivery efficiency of hyaluronic acid (HA), we designed and prepared glycodendron and pyropheophorbide-a (Ppa)-functionalized HA (HA-Ppa-Dendron) as a nanosystem for cancer photodynamic therapy. Linear Ppa-modified HA (HA-Ppa) was also prepared as a control. Cellular uptake of
An improved process for the synthesis of DMTMM-based coupling reagents
Raw SA
Tetrahedron Letters, 50(8), 946-948 (2009)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 749613-1G | 04061826653890 |
| 749613-5G | 04061833339671 |
