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About This Item
NACRES:
NA.23
UNSPSC Code:
12162002
material
PEG 3000
Quality Level
form
dispersion in H2O, nanoparticles
packaging
glass bottle of 1 mL
OD
50
diameter
10 nm
pH
6.0-8.0 (25 °C)
solubility
water: miscible
density
1.00 g/cm3
λmax
520 nm
functional group
carboxylic acid
storage temp.
2-8°C
General description
Carboxylic acid functionalized GNPs form conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.
Application
Carboxylic acid functionalized, PEG 3000, OD 50, and H2O dispersed gold nanoparticles (10 nm) (AuNPs) can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy. AUNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
The carboxylic acid group binds with various proteins and is used in targeted drug delivery and gene therapy.
Functionalized Particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Articles
最近出现的许多高功能纳米材料为癌症的认识、诊断和治疗提供了新的方案。
The recent emergence of a number of highly functional nanomaterials has enabled new approaches to the understanding, diagnosis, and treatment of cancer.
Biomaterials science integrates smart materials into biological research, requiring a deep understanding of biological systems.
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 765457-1ML | 04061837524110 |