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Merck
CN

779539

L-Cystine

Wacker Chemie AG, ≥98.5%

Synonym(s):

(R,R)-3,3′-Dithiobis(2-aminopropionic acid)

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About This Item

Linear Formula:
[-SCH2CH(NH2)CO2H]2
CAS Number:
Molecular Weight:
240.30
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-296-3
Beilstein/REAXYS Number:
1728094
MDL number:
Assay:
≥98.5%
Form:
powder
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Quality Level

assay

≥98.5%

form

powder

optical activity

[α]/D -224 to -218°

reaction suitability

reaction type: solution phase peptide synthesis

manufacturer/tradename

Wacker Chemie AG

impurities

≤0.02% ammonium, ≤0.2% ninhidrin positive substances (each), ≤10 ppm heavy metals

ign. residue

≤0.1%

loss

≤0.2% loss on drying

mp

>240 °C (dec.) (lit.)

anion traces

chloride (Cl-): ≤200 ppm, sulfate (SO42-): ≤300 ppm

cation traces

As: ≤1 ppm, Fe: ≤10 ppm, Pb: ≤5 ppm

suitability

clear, colorless for appearance of solution

SMILES string

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

LEVWYRKDKASIDU-IMJSIDKUSA-N

General description

L-Cystine is an amino acid mainly found in the keratin of hair.
This product is supplied from Wacker FERMOPURE® material, but is sold for R&D use only, not for drug, household or other uses.

Application

L-Cystine can be used as a starting material for the synthesis of d-biotin, aromatic-bridged cystine cyclic peptides (cystinophanes), chiral imidazolidine disulfides and biodegradable PEGylated gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) L-cystine copolymers.

Legal Information

FERMOPURE is a registered trademark of Wacker Chemie AG


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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PEG-g-poly (GdDTPA-co-L-cystine): a biodegradable macromolecular blood pool contrast agent for MR imaging.
Mohs A M, et al.
Bioconjugate Chemistry, 15(6), 1424-1430 (2004)
Cystinophanes, a novel family of aromatic-bridged cystine cyclic peptides: synthesis, crystal structure, molecular recognition, and conformational studies.
Ranganathan D, et al.
Journal of the American Chemical Society, 120(12), 2695-2702 (1998)
L-Cystine
Gortner RA and Hoffman WF
Organic Syntheses, 5, 39-39 (1925)



Global Trade Item Number

SKUGTIN
779539-100G04061838351937
779539-1KG04061826681060
779539-25KG04061833367575