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Merck
CN

78450

m-Phenylenediamine dihydrochloride

≥99.0% (AT)

Synonym(s):

1,3-Benzenediamine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H8N2 · 2HCl
CAS Number:
Molecular Weight:
181.06
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-790-0
Beilstein/REAXYS Number:
3911748
MDL number:
Assay:
≥99.0% (AT)
Form:
powder
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Quality Level

assay

≥99.0% (AT)

form

powder

SMILES string

Cl.Cl.Nc1cccc(N)c1

InChI

1S/C6H8N2.2ClH/c7-5-2-1-3-6(8)4-5;;/h1-4H,7-8H2;2*1H

InChI key

SVTOYMIYCMHPIV-UHFFFAOYSA-N

Application

m-Phenylenediamine dihydrochloride is used in the synthesis of bis(thiazolidone) and bis(thiohydantoin) derivatives. It can be used to increase the pore size in the fabrication of poly(aniline-co-1,3-phenylenediamine) cryogels.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Muta. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Effect of 1, 3-phenylenediamine concentration on the properties of poly (aniline-co-1, 3-phenylenediamine) cryogels.
Milakin K A, et al.
Materials Letters (2018)
SYNTHESIS OF BIS (THIAZOLIDONE) AND BIS (THIOHYDANTOIN) AND THEIR DERIVATIVES FROM M-PHENYLENEDIAMINE.
ACHARY T E, et al.
Chemischer Informationsdienst, 7(16) (1976)
Ariana Q Farrand et al.
Brain research, 1651, 88-94 (2016-10-30)
Mitochondrial dysfunction has been implicated in the degeneration of dopamine (DA) neurons in Parkinson's disease (PD). In addition, animal models of PD utilizing neurotoxins, such as 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, have shown that these toxins disrupt mitochondrial respiration by targeting complex



Global Trade Item Number

SKUGTIN
78450-500G04061832102931
78450-100G04061832946597