79229
N-Boc-1,6-hexanediamine
≥98.0% (NT)
Synonym(s):
N-Boc-1,6-diaminohexane, tert-Butyl-N-(6-aminohexyl)carbamate
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About This Item
Empirical Formula (Hill Notation):
C11H24N2O2
CAS Number:
Molecular Weight:
216.32
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2219107
Assay:
≥98.0% (NT)
Form:
liquid
Quality Level
assay
≥98.0% (NT)
form
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index
n20/D 1.462
density
0.965 g/mL at 20 °C (lit.)
functional group
Boc, amine
SMILES string
NCCCCCCNC(OC(C)(C)C)=O
InChI
1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)
InChI key
RVZPDKXEHIRFPM-UHFFFAOYSA-N
Application
N-Boc-1,6-hexanediamine can be used as a linear hexyl spacer (C6-spacer) to synthesize:
- Biodegradable poly(disulfide amine)s for gene delivery.
- A multifunctional dendrimer for theranostics.
- Polyamide platinum anti-cancer complexes designed to target cancer specific DNA sequences.
- Self-assembled monolayers (SAMs) that resist adsorption of proteins.
- [N-(6-(4-Hydroxy-6-isopropylamino-1,3,5-triazin-2-ylamino)hexyl)-5-hydroxy-1,4-naphthoquinone-3-propionamide] (JUG-HATZ), which can be used in designing electrochemical immunosensors.
Reagent for the introduction of a C6-spacer.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
257.0 °F - closed cup
flash_point_c
125 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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A label-free electrochemical immunosensor for direct, signal-on and sensitive pesticide detection.
Tran HV, et al.
Biosensors And Bioelectronics, 31(1), 62-68 (2012)
Haonan Xing et al.
Colloids and surfaces. B, Biointerfaces, 182, 110355-110355 (2019-07-16)
Inspired by the excellent membrane affinity of antimicrobial polymers, we synthesized a novel biodegradable poly(amino amine) polymer with pendent side chains that mimic the widely used biocide polyhexamethylene biguanide (PHMB) for gene delivery. Michael addition polymerization was utilized to form
Novel biodegradable poly (disulfide amine) s for gene delivery with high efficiency and low cytotoxicity.
Ou M, et al.
Bioconjugate Chemistry, 19(3), 626-633 (2008)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 79229-5G | 04061838076472 |
| 79229-1G | 04061832950761 |