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855987

D-Valine

Name: <SC>D</SC>-Valine
Brand: ALDRICH

≥98%, for peptide synthesis

Synonym(s):

(R)-α-Aminoisovaleric acid, D-2-Amino-3-methylbutanoic acid

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About This Item

Linear Formula:

(CH₃)₂CHCH(NH₂)CO₂H

CAS Number:

640-68-6

Molecular Weight:

117.15

NACRES:

NA.22

PubChem Substance ID:

24888396

UNSPSC Code:

12352209

EC Number:

211-368-9

MDL number:

MFCD00064219

Beilstein/REAXYS Number:

1721135

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Properties

Product Name

D-Valine, ≥98%

Quality Level

100

assay

≥98%

form

powder

optical activity

[α]23/D −32.0 to −24.0°, c = 8 in 6 M HCl

optical purity

ee: 99% (GLC)

reaction suitability

reaction type: solution phase peptide synthesis

mp

>295 °C (subl.) (lit.)

application(s)

peptide synthesis

SMILES string

CC(C)[C@@H](N)C(O)=O

InChI

1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1

InChI key

KZSNJWFQEVHDMF-SCSAIBSYSA-N

Description

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.

Kimberly A Smith et al.

American journal of respiratory cell and molecular biology, 53(3), 355-367 (2015-01-09)

Hypoxic pulmonary vasoconstriction (HPV) is an important physiological response that optimizes the ventilation/perfusion ratio. Chronic hypoxia causes vascular remodeling, which is central to the pathogenesis of hypoxia-induced pulmonary hypertension (HPH). We have previously shown that Notch3 is up-regulated in HPH

Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension.

Shanshan Song et al.

American journal of physiology. Cell physiology, 307(4), C373-C383 (2014-06-13)

An increase in cytosolic Ca(2+) concentration ([Ca(2+)]cyt) in pulmonary arterial smooth muscle cells (PASMC) is a major trigger for pulmonary vasoconstriction and an important stimulus for pulmonary arterial medial hypertrophy in patients with idiopathic pulmonary arterial hypertension (IPAH). Vascular smooth

Vitamin D reverses aPL-induced inflammation and LMWH-induced sFlt-1 release by human trophoblast.

Stefan M Gysler et al.

American journal of reproductive immunology (New York, N.Y. : 1989), 73(3), 242-250 (2014-07-30)

Women with antiphospholipid syndrome (APS) are at increased risk of recurrent pregnancy loss (RPL) and preeclampsia. Antiphospholipid antibodies (aPL) directly alter trophoblast function. Treatment with low molecular weight heparin (LMWH) reduces the risk of RPL but not preeclampsia. Moreover, LMWH

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Global Trade Item Number

SKU	GTIN
855987-25G	04061833026175
855987-5G	04061833026489