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857653

trans-4-(Aminomethyl)cyclohexanecarboxylic acid

Name: <I>trans</I>-4-(Aminomethyl)cyclohexanecarboxylic acid
Brand: ALDRICH

97%

Synonym(s):

AMCA, AMCHA, HAKU, TAMCHA, Tranexamic acid

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About This Item

Linear Formula:

H₂NCH₂C₆H₁₀CO₂H

CAS Number:

1197-18-8

Molecular Weight:

157.21

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24888448

EC Number:

214-818-2

Beilstein/REAXYS Number:

2207452

MDL number:

MFCD00001466

Assay:

97%

Form:

powder

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Properties

Quality Level

200

assay

97%

form

powder

mp

>300 °C (lit.)

functional group

amine, carboxylic acid

SMILES string

NC[C@H]1CC[C@@H](CC1)C(O)=O

InChI

1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-

InChI key

GYDJEQRTZSCIOI-LJGSYFOKSA-N

Gene Information

human ... PLG(5340)

Description

Application

Used as a lysine analogue to characterize binding sites in plasminogen.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Temporal organization of GABAergic interneurons in the intermediate CA1 hippocampus during network oscillations.

Thomas Forro et al.

Cerebral cortex (New York, N.Y. : 1991), 25(5), 1228-1240 (2013-11-28)

Travelling theta oscillations and sharp wave-associated ripples (SWRs) provide temporal structures to neural activity in the CA1 hippocampus. The contribution of rhythm-generating GABAergic interneurons to network timing across the septotemporal CA1 axis remains unknown. We recorded the spike-timing of identified

Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total hip replacement: a randomized controlled trial (TRANX-H).

Sattar Alshryda et al.

The Journal of bone and joint surgery. American volume, 95(21), 1969-1974 (2013-11-08)

Approximately one-third of patients undergoing total hip replacement surgery require one to three units of blood postoperatively. Tranexamic acid is a synthetic antifibrinolytic agent that has been successfully used intravenously to control bleeding after total hip replacement. A topical application

Topical (intra-articular) tranexamic acid reduces blood loss and transfusion rates following total knee replacement: a randomized controlled trial (TRANX-K).