912220
NanoFabTx™ PLGA-micro
for synthesis of 1-5 μm particles
Synonym(s):
NanoFabTx™ reagent kit, PLGA microparticle kit
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About This Item
NACRES:
NA.23
UNSPSC Code:
12161503
General description
The NanoFabTx™ PLGA-micro kit provides reagents (PLGA and stabilizer) and a protocol for microfluidic synthesis of microparticles between 1 to 5 μm. This reagent kit can be combined with the NanoFabTx™ Microfluidic - micro device kit (Cat.No. 911860) for microfluidic synthesis of PLGA micro particles.
Application
NanoFabTx™ PLGA-micro for synthesis of 1-5 μm particle reagent kit is designed for the synthesis of hydrophobic drug- encapsulated poly(lactic-co-glycolic acid) (PLGA) microparticles. The protocol gives users step-by-step instructions developed and tested by our formulation scientists. The protocol includes suggested conditions for incorporating drugs into the formulation and details how to tailor the parameters to yield 1 μm particles, 5 μm particles, or any size in between—all with low polydispersity. This kit affords scientists the synthetic control and reproducibility needed to encapsulate drugs, proteins, or other molecules with polymer microparticles of a chosen size and drug loading. With this kit, researchers can quickly identify the ideal microparticle size and drug loading for their research application. PLGA is a biocompatible and biodegradable polymer that has been widely used in drug delivery systems for controlled drug release of many different types of therapeutic molecules.
Features and Benefits
- Flexible synthesis tool to create uniform and reproducible nanoparticles
- Optimized to make microparticles 1-5 μm by microfluidics with low polydispersity
- Enables microparticle formulation screening and optimization of microparticles 1-5 μm to select ideal particle size for enhanced drug loading and controlled release
- Based on non-toxic, biodegradable polymers
Legal Information
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
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Storage Class
12 - Non Combustible Liquids
Regulatory Information
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Articles
Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.
NanoFabTx™ platform accelerates drug development with ready-to-use formulations and microfluidic devices for particle synthesis.
NanoFabTX kits enable precise drug delivery with lipid nanoparticles and liposomes for mRNA and nucleic acids.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 912220-1EA | 04061841722823 |
| 912220-1KT | 04065266037241 |