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Merck
CN

914886

Silica nanoparticles

pore size non-porous, 700 nm particle size, 5 % (w/w) in water, dispersion

Synonym(s):

Monodisperse silicon dioxide, Non-porous silica, Non-porous silicon dioxide, Silica

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About This Item

Empirical Formula (Hill Notation):
SiO2
CAS Number:
Molecular Weight:
60.08
UNSPSC Code:
12352309
NACRES:
NA.23
MDL number:
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Quality Level

form

dispersion, nanoparticles

concentration

5 % (w/w) in water

particle size

700 nm

pore size

non-porous

SMILES string

[Si](=O)=O

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

Application

Monodisperse nonporous silica nanoparticles find application in drug delivery and molecular imaging whereas micron sized particles are used in liquid chromatography. We offer highly monodisperse nonporous silica in aqueous soltion, with sizes varying from 150 nm to 900 nm. The high monodispersity of our particles makes them suitable for aforementioned applications.


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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Articles

Nonporous SiNPs are investigated as nanocarriers for drug delivery and smart plastics due to monodispersed particles.


Zhigang Xu et al.
Nanoscale, 7(13), 5859-5868 (2015-03-12)
A myriad of drug delivery systems such as liposomes, micelles, polymers and inorganic nanoparticles (NPs) have been developed for cancer therapy. Very few of them, however, have the ability to integrate multiple functionalities such as specific delivery, high circulation stability
Li Tang et al.
Nano today, 8(3), 290-312 (2013-09-03)
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to change the landscape of the diagnosis and therapy of many diseases. In the past several decades, the advancement in nanotechnology and material science has resulted in a large number
Martha Kim et al.
Scientific reports, 7(1), 8238-8238 (2017-08-16)
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in



Global Trade Item Number

SKUGTIN
914886-2ML04061842083770